Assay Image Detail

Contributor	Petiniot LK (J:62720)
Copyright	This image is from Petiniot, Proc Natl Acad Sci USA 2000 Jun 6;97(12):6664-9. Copyright 2000 National Academy of Sciences, U.S.A.

Genetic Changes
Mouse Chromosome	Name	Cytogenetic Type	Assay Type	Notes
1,17	T(17;1)	Translocation	SKY
12,15	T(12D-E;15A)	Translocation	SKY
12,15	Dic(12E;15E)	Dicentric chromosome	SKY
14	Dp(14)	Gain	SKY	Duplication of part of chromosome 14.
12,16	T(Dp16;12)	Translocation	SKY	Translocation of a duplicated portion of 16 and 12.

Model Details
MMHC ID MTB:36597 Tumor Name Leukocyte • lymphoma Treatment Type None (spontaneous) Tumor Synonyms malignant thymic lymphoma Organ Affected Thymus Frequency 25% Reference J:62720

Strain Details
Strain 129S-Atm^tm1Awb Rag2^tm1Fwa Strain Types targeted mutation (knockout) General Note Homozygous mutants were maintained on a 129S background that included contributions from at least 129S6/SvEvTac and 129S/SvEv-Gpi1^c. Strain Synonyms Rag2^-/- Atm^-/- Strain Sex Unspecified Reproductive Status reproductive status not specified Age of Onset 7 months Age of Detection 17.5 months