Tumor Frequency Grid (Inbred Strain Family x Organ)
Clicking in a colored box will take you to a summary of the records for
spontaneous tumors of that organ or organ system observed in inbred mice
of the corresponding strain family and reported in the literature. The data
represented in the grid is dynamically generated and reflects the most recent
data available in the MTB system.
The records will be sorted based on the highest reported frequency. This
summary, in turn, is linked to more detailed information about each of
the reported tumors.
Additional information associated with a colored cell will be displayed
in a popup window of your web browser when you hold your mouse over the
cell. (Requires JavaScript support.)
Legend
"Very High" - includes frequencies reported in the literature as being between
>80% and 100% as well as frequnecies reported to be "very high"
"High" - includes frequencies reported in the literature as being between
>50% and 80% as well as frequencies reported to be "high"
"Moderate" - includes frequencies reported in the literature as being between
>20% and 50% as well as frequencies reported to be "moderate"
"Low" - includes frequencies reported in the literature as being between
>10% and 20% as well as frequencies reported to be "low"
"Very Low" - includes frequencies reported in the literature as being between
>0% and 10% as well as frequencies reported to be "sporadic" and "very
low"
"Observed" - the literature reported that tumors were observed but the
authors did not indicate frequency
"Zero" - the literature reported that no tumors were observed
empty cell - no data in MTB
Notes
The colors of the cells are based on the highest reported frequency for
each strain family/organ or organ system combination.
The strain families used in this grid are grouped according to the mouse
strain genealogy published in Beck JA, Lloyd S, Hafezparast M, Lennon-Pierce
M, Eppig JT, Festing MFW, Fisher EMC. 2000. Nature Genetics 24: 23-25.
The strain genealogy chart from that reference may be accessed via http://www.informatics.jax.org/mgihome/genealogy/.