Pathology Image Detail

Caption

Adrenocortical adenoma. The kidney is in the upper left corner of this image. The adrenal gland has been subjected to immunohistochemistry for detection of expression of tyrosine hydroxylase. The center of the gland (adrenal medulla) is positive for this enzyme (dark brown). The cortex is blue due to the counterstain (hematoxylin). To the right of the medulla is an round mass that compresses the cortex. The cells resemble the cortex and do not express tyrosine hydroxylase and therefore are most likely of adrenal cortex origin.

Contributor

Sundberg J (J:94307)

Pathologist

Sundberg J (J:94307)

Method

IHC for tyrosine hydroxylase
Image Probes

Type: antibody

Name
anti-tyrosine hydroxylase
Target
tyrosine hydroxylase

Model

MMHC ID
MTB:11341
Tumor Name
Adrenal gland - Cortex • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
adrenocortical adenoma
Organ Affected
Adrenal gland - Cortex
Frequency
observed
Reference
J:94307

Strain

Strain
C3H/HeJ
Strain Types
inbred
Strain Synonyms
C3H/HeJ-MTV+
C3H The Jackson Laboratory
C3H/HeJ, H-2k
C3H
C3H/He
C3H/HeJ MMTV-
C3H Heston
C3
C3H/HeJ mtv+
MTV+
Strain Sex
Male
Reproductive Status
reproductive status not specified