Pathology Image Detail

Caption

This is a 40x image, 40x, that is a higher magnification of the right, middle region of the 4x image.

Description

adrenal gland spindle cell hyperplasia

Age at Necropsy

562 days

Notes

This is a group photomicrographs of the kidney and closely associated structures. The adrenal gland has spindle cell hyperplasia. The kidney has undergone degenerative changes in which the parenchyma has been compressed and destroyed by the increased back pressure of urine (hydronephrosis) caused by an inflammatory polp or papilloma within the ureter which effectively blocked drainage. While hard to find in tissue sections, these papillomatous lesions are not uncommonly associated with hydronephrosis in mouse kidneys, especially when unilateral.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:64312
Tumor Name
Adrenal gland • hyperplasia - spindle cell
Treatment Type
None (spontaneous)
Tumor Synonyms
adrenal gland spindle cell hyperplasia
Organ Affected
Adrenal gland
Frequency
observed
Reference
J:122261

Strain

Strain
C3B6F2
Strain Types
hybrid
General Note
The mouse is an F2 hybrid from a cross between a C3H/HeJ female with alopecia areata and a C57BL/6J male.
Strain Synonyms
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
562 days