Pathology Image Detail

Caption

This image was submitted by JM Ward. Image is from study set created by Herbert C. Morse III (NIAID, NIH), Torgny Fredrickson (NIAID, NIH), and Jerrold M. Ward (NCI, NIH) in 2001. This slide was immunostained for CD3. A whole-slide scan of this image can be viewed at https://images.jax.org/webclient/img_detail/15596.

Description

B-cell lymphoblastic lymphoma

Notes

Lymphoma, lymphoblastic, B-cell, lymph nodes .There is marked involvement of all mediastinal and other nodes and mediastinal tissue. The tumor cells are immature, uniform in size and have round nuclei with a nucleolus and little cytoplasm. There are scattered smaller mature lymphocytes. The tumor cells were CD45R+ and CD3-.

Contributor

Ward JM (J:107304)

Pathologist

Ward JM (J:107304)

Copyright

This work was supported in part with funds from the Mouse Model of Cancers Consortium, National Cancer Institute, National Institutes of health, and by contract N01-C056000 from the National cancer Institute.
Image Probes

Type: antibody

Name
anti-CD3 (SantaCruz)
Target
CD3
Supplier
Santa Cruz Biotechnology
Notes
Goat anti-human antibody.

Model

MMHC ID
MTB:69143
Tumor Name
Leukocyte - Lymphocyte - B-lymphocyte • lymphoma - lymphoblastic
Treatment Type
None (spontaneous)
Agents
Tumor Synonyms
B cell lymphoblastic lymphoma
Organ Affected
Leukocyte - Lymphocyte - B-lymphocyte
Frequency
observed
Reference
J:107304

Strain

Strain
NFS.V
Strain Types
congenic
General Note
NFS/N mice congenic for ecotropic murine leukemia virus (MuLV) induction loci from AKR and C58 mice.
Strain Synonyms
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified