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J:236843
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9 (of 9) pathology reports displayed, including 15 images.
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88546 Blood vessel   hemangiosarcoma Skin None (spontaneous)
(BALB/c x C57BL/6)F1
 Male reproductive status not specified observed 30 months dermal hemangiosarcoma J:236843
Image Caption:Fig. 5 "G. Dermal hemangiosarcoma from a 30-month-old male CB6F1."
6343
Image ID:6343
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 5 "H. Higher magnification of G. Irregular vascular channels are formed by atypical and anisokaryotic endothelial cells."
6344
Image ID:6344
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88543 Eye - Harderian gland   adenoma Eye - Harderian gland None (spontaneous)
(BALB/c x C57BL/6)F1
 Male reproductive status not specified observed 24 months Harderian gland adenoma J:236843
Image Caption:Fig. 3 "D. Hematoxylin and eosin-stained section of the Harderian gland adenoma from the CB6F1 mouse in panel 3B. The mutliobulated and expansible mass (M) is located in the retro-orbital space compresses the eye (E)."
6342
Image ID:6342
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Method / Stain:H&E
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88599 Leukocyte   lymphoma Spleen None (spontaneous)
(BALB/c x C57BL/6)F1
 Female reproductive status not specified observed 30 months pleomorphic/follicular malignant lymphoma in the spleen J:236843
Image Caption:Fig. "L. Higher magnification of K. Pleomorphic lymphoma can resemble HSA. Anatomic distribution, morphology, and immunohistochemistry can aid in differentiation."
6349
Image ID:6349
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 5 "K. Spleen with pleomorphic/follicular malignant lymphoma (*) from a 30-month-old CB6F1 female."
6348
Image ID:6348
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88522 Leukocyte - Monocyte - Macrophage - Histiocyte   histiocytic sarcoma Uterus None (spontaneous)
C57BL/6J
 Female reproductive status not specified observed 28 months histiocytic sarcoma (HSA) in the uterus J:236843
Image Caption:Fig. 5 "I. Uterus from a 28-month-old B6 mouse is effaced with histiocytic sarcoma (HSA). Broad ligament (arrow) and formed lumen (*) are indicated."
6335
Image ID:6335
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 5 "J. Higher magnification of HSA in I. Neoplastic histiocytes may have elongated oval to round nuclei or form multinucleated giant cells (inset). Myometrial smooth muscle (arrow) is indicated."
6336
Image ID:6336
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88578 Liver   hepatocellular carcinoma Liver None (spontaneous)
(BALB/c x C57BL/6)F1
 Female reproductive status not specified observed 30 months solid and trabecular hepatocellular carcinoma (HCC) J:236843
Image Caption:Fig. 5 "F. Higher magnification of trabecular HCC."
6347
Image ID:6347
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 5 "E. Liver with solid and trabecular hepatocellular carcinoma (HCC) from a 30-month-old female CB6F1."
6346
Image ID:6346
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88576 Lung   adenocarcinoma - mucinous Lung None (spontaneous)
(BALB/c x C57BL/6)F1
 Female reproductive status not specified observed 30 months mucinous pulmonary adenocarcinoma J:236843
Image Caption:Fig. 5B "Inset: Mucinous pulmonary adenocarcinoma from lungs pictures in Fig. 4G."
6345
Image ID:6345
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88541 Peritoneum - Mesentery   hyperplasia Peritoneum - Mesentery None (spontaneous)
C57BL/6J
 Unspecified reproductive status not specified observed 16-36 months hyperplastic mesenteric milky spot J:236843
Image Caption:Fig. 6 "Histological presentations of subclinical chronic systemic inflammation-associated lesions seen in C57BL/6 mice aged 16-36 months. A. Hyperplastic mesenteric milky spot."
6339
Image ID:6339
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88530 Pituitary gland - Pars distalis   adenocarcinoma Pituitary gland - Pars distalis None (spontaneous)
C57BL/6J
 Mixed Population reproductive status not specified 1% 28 months pituitary adenocarcinoma of the pars distalis in a female mouse J:236843
Image Caption:Fig. 5 "D. Higher magnification of the pituitary adenocarcinoma in C."
6338
Image ID:6338
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 5 "C. Decalcified cross-section of the head with a pituitary adenocarcinoma (P) of the pars distalis from mouse pictured in 2B. Pars distalis tumors typically are hemorrhagic and develop blood filled cystic spaces. Malignancy, in this case, was evident with invasion into the sphenoid bone (arrow). Brain (B), pituitary tumor (P) and ear (E) are indicated."
6337
Image ID:6337
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:88542 Tooth   dysplasia Tooth None (spontaneous)
C57BL/6J
 Unspecified reproductive status not specified observed 28 months incisor dysplasia J:236843
Image Caption:Fig. 7 "B. Higher magnification of the intrapulpal denticles. Denticles with an unusual presentation of a central column of ameloblasts (*) encircled with clear space, predentin (arrow, pink band) and odontoblasts (arrowhead). Denticles may represent dysplastic tooth development. Normal position of ameloblasts (*) and odontoblasts (arrow) are also indicated."
6341
Image ID:6341
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C
Image Caption:Fig. 7 "A. Decal cross-section of the nose and incisor roots (arrows) with unilateral multiple immature intrapulpal denticles from a 28-month-old B6 mouse."
6340
Image ID:6340
Source of Image:Pettan-Brewer C
Pathologist:Pettan-Brewer C