PDX Model DetailsTM00312

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PDX Model Summary

Model Details

Model ID (Previous ID)
TM00312 (PA0252F)
Initial Diagnosis
pancreatic ductal adenocarcinoma
Final Diagnosis
pancreatic ductal adenocarcinoma
Stage/Grade
Not Specified /
Primary Site
Pancreas
Sample Site
Pancreas
Tumor Type
Primary Malignancy

Patient

Sex
Male
Age (at time of tissue collection)
60
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve?
Yes
Current Smoker/Former Smoker
No / No

Engraftment

Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

no data

Gene CNV

no data

CNV Plots

no data

Tumor Mutation Burden

no data

Microsatellite Instability

no data

Gene Fusion

no data

Model Characterization

Histology

Summary:
P0 pathology consistent with mucinous adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F1882 for PDX model TM00312 stained for H&E.

P0 tumor F1882 for PDX model TM00312 stained for AE1AE3. Staining was positive.

P0 tumor F1882 for PDX model TM00312 stained for CD45. Staining was negative.

Dosing Studies

no data

Circos Plots

no data