PDX Model DetailsTM00314

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PDX Model Summary

Model Details

Model ID (Previous ID)
TM00314 (PA0258F)
Initial Diagnosis
pancreatic ductal adenocarcinoma
Final Diagnosis
pancreatic ductal adenocarcinoma
Stage/Grade
AJCC IIIA / Grade:2
Primary Site
Pancreas
Sample Site
Pancreas
Tumor Type
Primary Malignancy

Patient

Sex
Female
Age (at time of tissue collection)
77
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve?
Yes
Current Smoker/Former Smoker
Unknown / Unknown

Engraftment

Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

Platforms: hu133, stRNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Gene CNV

no data

CNV Plots

no data

Tumor Mutation Burden

no data

Microsatellite Instability

no data

Gene Fusion

no data

Model Characterization

Histology

Summary:
P1 pathology consistent with adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

Patient tumor for PDX model TM00314 (AKA, PA258) stained for H&E. This is a 4x image.

Patient tumor for PDX model TM00314 (AKA, PA258) stained for H&E. This is a 20x image.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for H&E.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for AE1AE3. Staining was positive.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for CD45. Staining was negative

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for KI67. Staining was positive.

Dosing Studies

no data

Circos Plots

no data