PDX Model DetailsTM01555

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PDX Model Summary

Model Details

Model ID (Previous ID)
TM01555 (TM01555F)
Initial Diagnosis
pancreatic carcinoma
Final Diagnosis
ampulla of Vater adenocarcinoma
Stage/Grade
AJCC IIB / Grade:2
Primary Site
ampulla of Vater
Sample Site
Pancreas
Tumor Type
Primary Malignancy

Patient

Sex
Male
Age (at time of tissue collection)
55
Race/Ethnicity
White / Not Reported
Treatment Naïve?
Yes
Current Smoker/Former Smoker
Unknown / Unknown

Engraftment

Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
Right Flank

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

Platforms: stRNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Gene CNV

no data

CNV Plots

no data

Tumor Mutation Burden

no data

Microsatellite Instability

no data

Gene Fusion

no data

Model Characterization

Histology

Summary:
P1 pathology consistent with pancreatic adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

Patient tumor for PDX model TM01555 stained with H&E.

P1 tumor F003 ID1009 for PDX model TM01555 stained with H&E.

P1 tumor F003 ID1009 for PDX model TM01555 stained for AE1AE3. Staining was positive.

P1 tumor F003 ID1009 for PDX model TM01555 stained for CD45. Staining was negative.

Dosing Studies

Circos Plots

no data