PDX Model DetailsJ000106560

Model Details	Model ID (Previous ID) J000106560 (PS4050) Primary Site Skin Tumor Site Skin Tumor Type Primary Malignancy Initial Diagnosis melanoma Final Diagnosis melanoma Stage/Grade IV /
Patient	Sex Male Age 79 Race/Ethnicity White / Not Hispanic or Latino Treatment Naïve Yes
Engraftment Host	Implantation Site Right Flank Sample Type Surgical resection (fragment)
Tumor Mutation Burden	Sample Sample PS4050 has a TMB score of 5.66 TMB Range 0.0-291.5 (across all JAX PDX models; TMB > 22 is considered high)
Microsatellite Instability	Sample Sample:PS4050 Score:MSI-S

Variant Summary

Platforms: stRNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Histology:

Summary:

P11 pathology is consistent with Melanoma.

Pathologist:

Dr. Regina Gandour-Edwards, University of California, Davis.

P11 tumor ID05 for PDX model J000106560 stained for AE1AE3. Staining was negative.

P11 tumor ID05 for PDX model J000106560 stained for S100. Staining was positive.