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PDX Model Details
Carcinoma: Urothelial carcinoma
bladder transitional cell carcinoma
Stage / Grade:
AJCC III / Grade:high
Race / Ethnicity:
White / Not Hispanic or Latino
(aka NSG or NOD Scid gamma)
Surgical resection (fragment)
Publications citing this model
Variant Summary currently not available.
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations.
High concordance of patient tumor morphology with P0 PDX tumor.
Dr. Regina Gandour-Edwards, University of California, Davis
Patient tumor for PDX model TM00020. Nests of high grade urothelial carcinoma invading bladder muscle wall.
P0 tumor #1233 for PDX model TM00020. Sheets of high grade urothelial carcinoma cells.
P0 tumor #1235 for PDX model TM00020. Negative staining of tumor cells for vimentin. Scattered positive cells (lymphocytes).
P0 tumor #1235 for PDX model TM00020. Positive staining for Ki67 indicating tumor cells of human origin.
Circos plot for P0 tumor #1232 for TM00020
Circos plot for P1 tumor # 0001 from PDX model TM00020