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PDX Model Details
Carcinoma: Urothelial carcinoma
bladder urothelial papillary carcinoma
Stage / Grade:
AJCC 0 - in situ / Grade:high
Race / Ethnicity:
White / Not Hispanic or Latino
(aka NSG or NOD Scid gamma)
Surgical resection (fragment)
Publications citing this model
Tumor Mutation Burden
Sample from passage P0 has a TMB score of 5.66
TMB Range:0.81-305.22 (across all JAX PDX models)
TMB > 22 is considered high.
Variant Summary currently not available.
P2 pathology consistent with high grade urothelial carcinoma.
Dr. Regina Gandour-Edwards, University of California, Davis.
Patient tumor for PDX model TM00025.
P0 tumor for PDX model TM00025.
P2 tumor F1820 ID002 for PDX model TM00025 stained for H&E.
P2 tumor F1820 ID002 for PDX model TM00025 stained for AE1/AE3. Staining was positive.
P2 tumor F1820 ID002 for PDX model TM00025 stained for CD45. Staining was negative.
P2 tumor F1820 ID002 for PDX model TM00025 stained for Ki67. Staining was positive.