PDX Model DetailsTM00312

Request more information on this PDX model.

Model Details

Model ID (Previous ID)
TM00312 (PA0252F)
Primary Site
Pancreas
Tumor Site
Pancreas
Tumor Type
Primary Malignancy
Initial Diagnosis
pancreatic ductal adenocarcinoma
Final Diagnosis
pancreatic ductal adenocarcinoma
Stage/Grade
Not Specified /

Patient

Sex
Male
Age
60
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve
Yes

Engraftment Host

Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)

Variant Summary

Gene Expression

No gene expression data currently available.

Gene CNV

No gene CNV data currently available.

CNV Plots

No gene CNV plots currently available.

Model Characterization

Histology: Summary:
P0 pathology consistent with mucinous adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F1882 for PDX model TM00312 stained for H&E.

P0 tumor F1882 for PDX model TM00312 stained for AE1AE3. Staining was positive.

P0 tumor F1882 for PDX model TM00312 stained for CD45. Staining was negative.

Dosing Studies