PDX Model DetailsTM00314

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Model Details

Model ID (Previous ID)
TM00314 (PA0258F)
Primary Site
Pancreas
Tumor Site
Pancreas
Tumor Type
Primary Malignancy
Initial Diagnosis
pancreatic ductal adenocarcinoma
Final Diagnosis
pancreatic ductal adenocarcinoma
Stage/Grade
AJCC IIIA / Grade:2

Patient

Sex
Female
Age
77
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve
Yes

Engraftment Host

Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)

Variant Summary

Gene Expression

Platforms: hu133, stRNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Gene CNV

No gene CNV data currently available.

CNV Plots

No gene CNV plots currently available.

Model Characterization

Histology: Summary:
Adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

Patient tumor for PDX model TM00314 (AKA, PA258) stained for H&E. This is a 4x image.

Patient tumor for PDX model TM00314 (AKA, PA258) stained for H&E. This is a 20x image.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for H&E.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for AE1AE3. Staining was positive.

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for CD45. Staining was negative

P1 tumor F006 P0063 P1 for PDX model TM00314 stained for KI67. Staining was positive.

Dosing Studies