Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM00339 Previous ID:SK129862F
Primary Site:Skin Initial Diagnosis:melanoma Final Diagnosis:melanoma
Tumor Site:Ovary Tumor Type:Metastatic Stage / Grade:AJCC IV /
Sex:Female Age: Race / Ethnicity:Not Reported / Not Reported
Treatment Naive:Yes
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site: Sample Type:Surgical resection (fragment)
Tumor Mutation Burden
Sample from passage P0 has a TMB score of 67.83
TMB Range:0.81-305.22  (across all JAX PDX models)
TMB > 22 is considered high.
Microsatellite Instability Help
Sample:SK129862F002P0     Score:MSI-S
Variant Summary Help

Gene Expression Help Platforms:hu133, stRNA_Seq
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
CNV Plots Help
Model Characterization
Histology: Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P2 tumor F0021 ID013 for PDX model TM00339 stained for H&E.

P2 tumor F0021 ID013 for PDX model TM00339 stained for AE1AE3. Staining was negative.

P2 tumor F0021 ID013 for PDX model TM00339 stained for CD45. Staining was negative.
Dosing Studies: