Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-09-15
MTB 3.0
 
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM01212 Previous ID:TM01212F
Primary Site:Pancreas Initial Diagnosis:pancreas adenocarcinoma Final Diagnosis:pancreas adenocarcinoma
Tumor Site:Pancreas Tumor Type:Not Specified Stage / Grade:Not Specified /
Patient
Sex:Male Age: Race / Ethnicity:Not Reported / Not Reported
Treatment Naive:Unknown
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site: Sample Type:Not Specified
Tumor Mutation Burden
Sample from passage P0 has a TMB score of 4.04
Sample from passage P1 has a TMB score of 3.23
TMB Range:0.81-305.22  (across all JAX PDX models)
TMB > 22 is considered high.
Variant Summary Help

Gene Expression Help Platforms:RNA_Seq
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
CNV Plots Help
Model Characterization
Histology: Summary:
Pancreatic adenocarcinoma with fidelity to P1.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F463 for PDX model TM01212 stained for H&E.

P1 tumor F463 ID306 for PDX model TM01212 stained for H&E.

P1 tumor F463 ID306 for PDX model TM01212 stained for AE1AE3. Staining was positive.

P1 tumor F463 ID306 for PDX model TM01212 stained for CD45. Staining was negative.

P2 tumor F463 ID012 for PDX model TM01212 stained for H&E.

P2 tumor F463 ID012 for PDX model TM01212 stained for AE1AE3. Staining was positive.

P2 tumor F463 ID012 for PDX model TM01212 stained for Ki67. Staining was positive.

P2 tumor F463 ID012 for PDX model TM01212 stained for CD45. Staining was negative.