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Last Database Update
2020-02-16
MTB 3.0
 
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM01555 Previous ID:TM01555F
Primary Site:ampulla of Vater Initial Diagnosis:pancreatic carcinoma Final Diagnosis:ampulla of Vater adenocarcinoma
Tumor Site:Pancreas Tumor Type:Primary Malignancy Stage / Grade:AJCC IIB / Grade:2
Patient
Sex:Male Age:55 Race / Ethnicity:White / Not Reported
Treatment Naive:Yes
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site:Right Flank Sample Type:Surgical resection (fragment)
Variant Summary Help

Gene Expression Help Platforms:stRNA_Seq
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
No gene CNV data currently available.
CNV Plots Help
No gene CNV plots currently available.
Model Characterization
Histology: Summary:
Pancreatic adenocarcinoma with fidelity to P1.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

Patient tumor for PDX model TM01555 stained with H&E.

P1 tumor F003 ID1009 for PDX model TM01555 stained with H&E.

P1 tumor F003 ID1009 for PDX model TM01555 stained for AE1AE3. Staining was positive.

P1 tumor F003 ID1009 for PDX model TM01555 stained for CD45. Staining was negative.
Dosing Studies: