PDX Model DetailsTM01555

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PDX Model Summary
Model Details	Model ID (Previous ID) TM01555 (TM01555F) Initial Diagnosis Pancreatic carcinoma Final Diagnosis Ampulla of Vater adenocarcinoma Stage/Grade AJCC IIB / Grade:2 Primary Site Ampulla of Vater Sample Site Pancreas Tumor Type Primary Malignancy
Patient	Sex Male Age (at time of tissue collection) 55 Race/Ethnicity White / Not Reported Treatment Naïve? Yes Current Smoker/Former Smoker Unknown / Unknown
Engraftment	Host Strain NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ (aka NSG or NOD Scid gamma) Sample Type Surgical resection (fragment) Engraftment Site Right Flank

Molecular Data (Engrafted Tumor)
Variants	no variation plots
Gene Expression	Platforms: stRNA_Seq Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV	no CNV data
CNV Plots	no CNV plots
Tumor Mutation Burden	no data
Microsatellite Instability	no data
Gene Fusion	no data

Model Characterization

Histology

Summary:
P1 pathology consistent with pancreatic adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

Patient tumor for PDX model TM01555 stained with H&E.	P1 tumor F003 ID1009 for PDX model TM01555 stained with H&E.
P1 tumor F003 ID1009 for PDX model TM01555 stained for AE1AE3. Staining was positive.	P1 tumor F003 ID1009 for PDX model TM01555 stained for CD45. Staining was negative.

Dosing Studies

Circos Plots

no data