Reference SummaryHeston WE, 1963;():247-68

Title

Genetics of Neoplasia

Authors

Heston WE

Journal

Volume

Issue

Year

1963

Pages

247-68

Abstract

Strain Notes

Strain Note
BALB/c Mice were NOT carriers of infectious MMTV.

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
NH Adrenal gland - Cortex adenoma Adrenal gland - Cortex

high

NH Adrenal gland - Cortex carcinoma
  • castration
Adrenal gland - Cortex

high

CE Adrenal gland - Cortex tumor
  • castration
Adrenal gland - Cortex

high

BALB/c Blood vessel hemangioendothelioma
  • o-aminoazotoluene
Blood vessel

high

HR Hrhr Blood vessel hemangioendothelioma
  • 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)
Blood vessel

54.0 - 76.0

C3H Eye - Harderian gland tumor Eye - Harderian gland

observed

C57L Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

25

C58 Leukocyte leukemia Leukocyte

high

AKR Leukocyte leukemia Leukocyte

high

C3Hf Liver hepatoma
  • diethylstilbestrol (DES)
Liver

72

C3H Liver hepatoma Liver

85

C3HeB Liver hepatoma Liver

30 - 91

A Lung tumor Lung

90

SWR Lung tumor Lung

80

BALB/c Lung tumor Lung

26 - 29

BL Lung tumor Lung

26

C3H Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

100

A Mammary gland tumor Mammary gland

low - high

DBA Mammary gland tumor Mammary gland

high

RIII Mammary gland tumor Mammary gland

high

BALB/c Mammary gland tumor Mammary gland

low

BALB/c Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

high

CC57BR Mammary gland tumor Mammary gland

0

CC57BR Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

55

CC57W Mammary gland tumor Mammary gland

0

CC57W Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

55

CBA Mesodermal cell/mesoblast sarcoma
  • methylcholanthrene (MCA)
Mesodermal cell/mesoblast

high

A Myoepithelial cell myoepithelioma Myoepithelial cell

observed

BALB/c Myoepithelial cell myoepithelioma Myoepithelial cell

observed

C3HeB Ovary tumor Ovary

29 - 47

C57BL Pituitary gland adenoma
  • estrogen
Pituitary gland

very high

HR Hrhr/+ Skin carcinoma
  • methylcholanthrene (MCA)
Skin

high

HR Hrhr Skin carcinoma
  • methylcholanthrene (MCA)
Skin

high

HR Hrhr Skin papilloma
  • methylcholanthrene (MCA)
Skin

100

HR Hrhr/+ Skin papilloma
  • methylcholanthrene (MCA)
Skin

100

129 Testis - Germ cell teratoma Testis - Germ cell

1

BALB/c Testis - Leydig cell (Interstitial cell) tumor
  • diethylstilbestrol (DES)
Testis - Leydig cell (Interstitial cell)

high

A Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
Testis - Leydig cell (Interstitial cell)

observed