Reference SummaryDeringer MK, J Natl Cancer Inst 1962;28():203-210

Title

Development of tumors, especially mammary tumors, in agent-free strain DBA/2eB mice

Authors

Deringer MK

Journal

J Natl Cancer Inst

Volume

28

Issue

Year

1962

Pages

203-210

Abstract

Links

J:2414 – MGI References
13885590 – National Library of Medicine/PubMed

Strain Notes

Strain Note
C3HeB Mice were NOT carriers of infectious MMTV.
DBA/2eBDe Mice were NOT carriers of infectious MMTV.
DBA/2Lw Mice were carriers of infectious MMTV.

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
DBA/2eBDe Adrenal gland - Cortex tumor Adrenal gland - Cortex

0 - 1.3

DBA/2eBDe Blood vessel hemangioendothelioma Blood vessel

6.7 - 16

DBA/2eBDe Eye - Harderian gland tumor Eye - Harderian gland

0 - 2.0

DBA/2eBDe Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0 - 1.3

DBA/2eBDe Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor
  • diethylstilbestrol (DES)
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0

DBA/2eBDe Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

0 - 7.8

DBA/2eBDe Leukocyte - Lymphocyte lymphohematopoietic neoplasm
  • diethylstilbestrol (DES)
Leukocyte - Lymphocyte

1.7

DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

9.8 - 12

DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

6.7 - 18

DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type B
  • diethylstilbestrol (DES)
Leukocyte - Lymphocyte

3.3

DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell

0 - 1.3

DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor
  • diethylstilbestrol (DES)
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell

1.7

DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

0 - 2.0

DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic
  • diethylstilbestrol (DES)
Leukocyte - Myelocyte (Granulocyte)

0

DBA/2eBDe Liver hepatoma Liver

0 - 5.3

DBA/2eBDe Liver hepatoma
  • diethylstilbestrol (DES)
Liver

5

DBA/2eBDe Lung hyperplasia Lung

0 - 3.9

DBA/2eBDe Lung hyperplasia
  • diethylstilbestrol (DES)
Lung

1.7

DBA/2eBDe Lung tumor Lung

1.3 - 3.9

DBA/2eBDe Mammary gland adenoacanthoma Mammary gland

0

C3HeB/De Mammary gland adenoacanthoma Mammary gland

observed

DBA/2Lw Mammary gland adenoacanthoma Mammary gland

observed

DBA/2Lw Mammary gland adenocarcinoma - mixed Mammary gland

observed

DBA/2eBDe Mammary gland adenocarcinoma - mixed Mammary gland

1.3

DBA/2eBDe Mammary gland adenocarcinoma - type A Mammary gland

2.7

DBA/2Lw Mammary gland adenocarcinoma - type A Mammary gland

observed

DBA/2eBDe Mammary gland adenocarcinoma - type B Mammary gland

5.9 - 25

DBA/2eBDe Mammary gland adenocarcinoma - type B
  • diethylstilbestrol (DES)
Mammary gland

1.7

C3HeB Mammary gland adenocarcinoma - type B Mammary gland

observed

DBA/2Lw Mammary gland adenocarcinoma - type B Mammary gland

observed

DBA/2eBDe Mammary gland adenocarcinoma - type C Mammary gland

2.6

DBA/2Lw Mammary gland carcinosarcoma Mammary gland

observed

DBA/2Lw Mammary gland tumor Mammary gland

77

C57BL/He Mammary gland tumor Mammary gland

0

DBA/2eBDe Mammary gland tumor Mammary gland

32

C3HeB/De Mammary gland tumor Mammary gland

4 - 74

C3HeB/De Mammary gland tumor
  • diethylstilbestrol (DES)
Mammary gland

22

C3H/He Mammary gland tumor Mammary gland

94

DBA/2eBDe Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

0 - 3.9

DBA/2eBDe Muscle - Smooth leiomyoma Uterus

0 - 1.3

DBA/2eBDe Skin gland - Sebaceous gland tumor
  • diethylstilbestrol (DES)
Skin gland - Sebaceous gland

1.7

DBA/2eBDe Skin squamous cell carcinoma Skin

0 - 3.9

DBA/2eBDe Stomach squamous cell carcinoma
  • diethylstilbestrol (DES)
Stomach

1.7

DBA/2eBDe Testis - Leydig cell (Interstitial cell) tumor
  • diethylstilbestrol (DES)
Testis - Leydig cell (Interstitial cell)

1.7

DBA/2eBDe Uterus - Endometrium tumor Uterus - Endometrium

0 - 2.0

DBA/2eBDe Uterus tumor Uterus

0 - 2.6