Reference SummaryHeston WE, J Natl Cancer Inst 1960;24():425-435

Title

High incidence of spontaneous hepatomas and the increase of this incidence with urethan in C3H, C3Hf, and C3He male mice

Authors

Heston WE; Vlahakis G; Deringer MK

Journal

J Natl Cancer Inst

Volume

24

Issue

Year

1960

Pages

425-435

Abstract

Links

J:2433 – MGI References
14401531 – National Library of Medicine/PubMed

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
C3HeB/De Blood vessel hemangioendothelioma
  • urethane (ethyl carbamate)
Peritoneum - Mesentery

1.4

C3H/He Liver hepatoma
  • urethane (ethyl carbamate)
Liver

79.5 - 92.6

C3H/He Liver hepatoma Liver

85.3

C3Hf/He Liver hepatoma
  • urethane (ethyl carbamate)
Liver

90 - 94.6

C3Hf/He Liver hepatoma Liver

71.9

C3Hf/He Liver hepatoma
  • Purina laboratory chow
Liver

57.4

C3HeB/De Liver hepatoma
  • urethane (ethyl carbamate)
Liver

89 - 91.4

C3HeB/De Liver hepatoma Liver

78.5

C3H/He Lung tumor
  • urethane (ethyl carbamate)
Lung

62.1 - 100

C3H/He Lung tumor Lung

7.8

C3Hf/He Lung tumor
  • urethane (ethyl carbamate)
Lung

54.8 - 97.5

C3Hf/He Lung tumor Lung

10.4

C3Hf/He Lung tumor
  • Purina laboratory chow
Lung

4.6

C3HeB/De Lung tumor
  • urethane (ethyl carbamate)
Lung

57.5 - 100

C3HeB/De Lung tumor Lung

12.7

C3Hf/He Skin papilloma
  • urethane (ethyl carbamate)
Skin

1.3

C3Hf/He Skin squamous cell carcinoma
  • urethane (ethyl carbamate)
Skin

1.3

C3H/He (Unspecified organ) reticulum cell neoplasm (Unspecified organ)

1.0

C3Hf/He (Unspecified organ) reticulum cell neoplasm
  • urethane (ethyl carbamate)
(Unspecified organ)

1.1