Reference SummaryAkamatsu Y, J Natl Cancer Inst 1974 Feb;52(2):377-85

Title

Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.

Authors

Akamatsu Y; Barton BP

Journal

J Natl Cancer Inst

Volume

52

Issue

2

Year

1974

Pages

377-85

Abstract

Links

4361176 – National Library of Medicine/PubMed

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
BT/Os Forestomach keratoacanthoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

12 - 15

C57BL/6Os Forestomach keratoacanthoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0 - 2.4

BALB/cOs Forestomach keratoacanthoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0

C3HeB/Os Forestomach keratoacanthoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

6.3 - 11

C3H/HeOs Forestomach keratoacanthoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0 - 8.3

BALB/cOs Forestomach papilloma Forestomach

1.0 - 5.6

BT/Os Forestomach squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

5 - 31

C57BL/6Os Forestomach squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0

BALB/cOs Forestomach squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0

C3HeB/Os Forestomach squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0 - 4.3

C3H/HeOs Forestomach squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

0

BT/Os Forestomach squamous cell papilloma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

10 - 24

C57BL/6Os Forestomach squamous cell papilloma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

13 - 20

BALB/cOs Forestomach squamous cell papilloma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

11 - 14

C3HeB/Os Forestomach squamous cell papilloma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

19 - 31

C3H/HeOs Forestomach squamous cell papilloma
  • 3-methylcholanthrene (MCA) (3-MC)
Forestomach

12 - 17

BT/Os Forestomach tumor Forestomach

0

C57BL/6Os Forestomach tumor Forestomach

0

C3HeB/Os Forestomach tumor Forestomach

0

C3H/HeOs Forestomach tumor Forestomach

0

BT/Os Leukocyte leukemia Leukocyte

1.7

BT/Os Leukocyte lymphoma Leukocyte

4.3

BT/Os Leukocyte lymphoma
  • 3-methylcholanthrene (MCA) (3-MC)
Leukocyte

0 - 5

C57BL/6Os Leukocyte lymphoma Leukocyte

2.5 - 5.6

C57BL/6Os Leukocyte lymphoma
  • 3-methylcholanthrene (MCA) (3-MC)
Leukocyte

11 - 25

BALB/cOs Leukocyte lymphoma Leukocyte

5.6 - 13

BALB/cOs Leukocyte lymphoma
  • 3-methylcholanthrene (MCA) (3-MC)
Leukocyte

31 - 47

C3HeB/Os Leukocyte lymphoma Leukocyte

4.9 - 6.2

C3HeB/Os Leukocyte lymphoma
  • 3-methylcholanthrene (MCA) (3-MC)
Leukocyte

3.1 - 5.7

C3H/HeOs Leukocyte lymphoma Leukocyte

0 - 1.2

C3H/HeOs Leukocyte lymphoma
  • 3-methylcholanthrene (MCA) (3-MC)
Leukocyte

4.2 - 9.3

BT/Os Liver hepatoma Liver

1.1 - 11

BT/Os Liver hepatoma
  • 3-methylcholanthrene (MCA) (3-MC)
Liver

0 - 3.9

C57BL/6Os Liver hepatoma Liver

0 - 10

C57BL/6Os Liver hepatoma
  • 3-methylcholanthrene (MCA) (3-MC)
Liver

0 - 1.2

BALB/cOs Liver hepatoma Liver

0 - 1.9

BALB/cOs Liver hepatoma
  • 3-methylcholanthrene (MCA) (3-MC)
Liver

2.4 - 2.8

C3HeB/Os Liver hepatoma Liver

0 - 18

C3HeB/Os Liver hepatoma
  • 3-methylcholanthrene (MCA) (3-MC)
Liver

0 - 2.9

C3H/HeOs Liver hepatoma Liver

0 - 34

C3H/HeOs Liver hepatoma
  • 3-methylcholanthrene (MCA) (3-MC)
Liver

0 - 4.2

BT/Os Lung - Alveolus adenoma Lung - Alveolus

1.1 - 2.2

BT/Os Lung - Alveolus adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung - Alveolus

3.9

C57BL/6Os Lung - Alveolus adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung - Alveolus

1.2 - 5

BALB/cOs Lung - Alveolus adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung - Alveolus

50 - 62

BALB/cOs Lung - Alveolus adenoma Lung - Alveolus

1.0

C3HeB/Os Lung - Alveolus adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung - Alveolus

2.9

C3HeB/Os Lung - Alveolus adenoma Lung - Alveolus

3.1

BT/Os Lung adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung

0

C57BL/6Os Lung adenoma Lung

0

BALB/cOs Lung adenoma Lung

0

C3HeB/Os Lung adenoma Lung

0

C3HeB/Os Lung adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung

0

C3H/HeOs Lung adenoma Lung

0

C3H/HeOs Lung adenoma
  • 3-methylcholanthrene (MCA) (3-MC)
Lung

0 - 4.2

BT/Os Mammary gland tumor Mammary gland

70

BT/Os Mammary gland tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Mammary gland

85

C57BL/6Os Mammary gland tumor Mammary gland

0

C57BL/6Os Mammary gland tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Mammary gland

0

BALB/cOs Mammary gland tumor Mammary gland

12

BALB/cOs Mammary gland tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Mammary gland

24

C3HeB/Os Mammary gland tumor Mammary gland

2.1

C3HeB/Os Mammary gland tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Mammary gland

6.3

C3H/HeOs Mammary gland tumor Mammary gland

96

C3H/HeOs Mammary gland tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Mammary gland

93

BT/Os Ovary tumor Ovary

1.7

BT/Os Ovary tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Ovary

0

C57BL/6Os Ovary tumor Ovary

0

C57BL/6Os Ovary tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Ovary

0

BALB/cOs Ovary tumor Ovary

3.8

BALB/cOs Ovary tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Ovary

4.8

C3HeB/Os Ovary tumor Ovary

2.1

C3HeB/Os Ovary tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Ovary

12.5

C3H/HeOs Ovary tumor Ovary

0

C3H/HeOs Ovary tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Ovary

0

BT/Os Skin tumor Skin

1.1 - 2.2

BT/Os Skin tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Skin

3.9 - 5

C57BL/6Os Skin tumor Skin

0

C57BL/6Os Skin tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Skin

3.5 - 5

BALB/cOs Skin tumor Skin

0 - 3.8

BALB/cOs Skin tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Skin

2.4 - 2.8

C3HeB/Os Skin tumor Skin

0

C3HeB/Os Skin tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Skin

0 - 6.3

C3H/HeOs Skin tumor Skin

0

C3H/HeOs Skin tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Skin

0 - 8.3

BT/Os Urinary bladder squamous cell carcinoma
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

3.9

BT/Os Urinary bladder tumor Urinary bladder

0

BT/Os Urinary bladder tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

0

C57BL/6Os Urinary bladder tumor Urinary bladder

0

C57BL/6Os Urinary bladder tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

0

BALB/cOs Urinary bladder tumor Urinary bladder

0

BALB/cOs Urinary bladder tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

0

C3HeB/Os Urinary bladder tumor Urinary bladder

0

C3HeB/Os Urinary bladder tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

0

C3H/HeOs Urinary bladder tumor Urinary bladder

0

C3H/HeOs Urinary bladder tumor
  • 3-methylcholanthrene (MCA) (3-MC)
Urinary bladder

0