Reference SummaryDeringer MK, J Natl Cancer Inst 1959;22():995-1002

Title

 Occurrence of tumors, particularly mammary tumors, in agent-free strain C3HeB mice

Authors

 Deringer MK

Journal

 J Natl Cancer Inst

Volume

 22

Issue

Year

 1959

Pages

 995-1002

Abstract

Links

 J:24689 – MGI References
13655075 – National Library of Medicine/PubMed

Strain Notes

Strain Note
C3HeB/De Mice were NOT carriers of infectious MMTV.
C3Hf/2He Mice were NOT carriers of infectious MMTV.
C3Hf/An Mice were NOT carriers of infectious MMTV.
C3Hff/He Mice were NOT carriers of infectious MMTV.
C3Hf/He Mice were NOT carriers of infectious MMTV.
C3H/He Mice were carriers of infectious MMTV.

Models
Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
C3HeB/De Adrenal gland - Cortex adenoma
  • diethylstilbestrol (DES)
 Adrenal gland - Cortex

1.0
C3HeB/De Adrenal gland - Cortex adenoma Adrenal gland - Cortex

4.8
C3HeB/De Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.2
C3HeB/De Blood vessel hemangioendothelioma Blood vessel

1.2 - 5.2
C3HeB/De Blood vessel hemangioendothelioma
  • diethylstilbestrol (DES)
 Blood vessel

3.1
C3HeB/De Eye - Harderian gland tumor Eye - Harderian gland

4.8
C3HeB/De Kidney carcinoma
  • diethylstilbestrol (DES)
 Kidney

1.0
C3HeB/De Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

1.2
C3HeB/De Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

1.0
C3HeB/De Leukocyte - Lymphocyte lymphohematopoietic neoplasm
  • diethylstilbestrol (DES)
 Leukocyte - Lymphocyte

1.0
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

0.6 - 2.0
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type A
  • diethylstilbestrol (DES)
 Leukocyte - Lymphocyte

2.0
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

1.9
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type B
  • diethylstilbestrol (DES)
 Leukocyte - Lymphocyte

1.0
C3HeB/De Liver hepatoma Liver

30 - 90
C3HeB/De Liver hepatoma
  • diethylstilbestrol (DES)
 Liver

55
C3HeB/De Lung tumor Lung

3.7 - 24
C3HeB/De Lung tumor
  • diethylstilbestrol (DES)
 Lung

10
C3HeB/De Mammary gland adenoacanthoma Mammary gland

17 - 28
C3HeB/De Mammary gland adenocarcinoma - type A Mammary gland

17 - 26
C3HeB/De Mammary gland adenocarcinoma - type A
  • diethylstilbestrol (DES)
 Mammary gland

10
C3HeB/De Mammary gland adenocarcinoma - type B Mammary gland

4.0 - 28
C3HeB/De Mammary gland adenocarcinoma - type B
  • diethylstilbestrol (DES)
 Mammary gland

12
C3HeB/De Mammary gland tumor Mammary gland

4.0 - 74
C3H/He Mammary gland tumor
  • MMTV - mouse mammary tumor virus
 Mammary gland

94
C3HeB/De Mammary gland tumor
  • diethylstilbestrol (DES)
 Mammary gland

22
C3Hf/He Mammary gland tumor Mammary gland

2 - 63
C3Hf/He Mammary gland tumor
  • diethylstilbestrol (DES)
 Mammary gland

20
C3Hf/An Mammary gland tumor Mammary gland

3 - 27
C3Hff/He Mammary gland tumor Mammary gland

29
C3Hf/2He Mammary gland tumor Mammary gland

51
C3Hf/He Mammary gland tumor
  • estrogen
  • castration
 Mammary gland

37 - 71
C3HeB/De Mammary gland tumor
  • estrogen
  • castration
 Mammary gland

61 - 69
C3HeB/De Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1.2 - 7.1
C3HeB/De Mesodermal cell/mesoblast sarcoma Uterus

3.0
C3HeB/De Mesodermal cell/mesoblast sarcoma
  • diethylstilbestrol (DES)
 Mesodermal cell/mesoblast

4.1
C3HeB/De Myoepithelial cell myoepithelioma Myoepithelial cell

1.2
C3HeB/De Ovary - Granulosa cell tumor Ovary - Granulosa cell

13 - 23
C3HeB/De Ovary adenoma - tubular Ovary

14 - 25
C3HeB/De Ovary luteoma Ovary

0.6 - 2.0
C3HeB/De Ovary tumor Ovary

1.2
CE/Wy Ovary tumor Ovary

33
CE/WyDi Ovary tumor Ovary

52
C3Hf/He Ovary tumor Ovary

5.0 - 10.0
C3HeB/De Ovary tumor - mixed Ovary

0.6 - 2.0
C3HeB/De Skin papilloma Skin

0.6
C3HeB/De Uterus polyp Uterus

1.2 - 4.0
C3HeB/De (Unspecified organ) squamous cell carcinoma (Unspecified organ)

0.6