Reference SummaryDiwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Title

Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. 3. Association between infectious or subinfectious endogenous type-C RNA tumor virus expression and chemically induced tumorigenesis.

Authors

Diwan BA; Meier H; Huebner RJ

Journal

J Natl Cancer Inst

Volume

51

Issue

6

Year

1973

Pages

1965-70

Abstract

Links

J:24831 – Mouse Genome Informatics
4358152 – National Library of Medicine/PubMed

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
C57L/J Leukocyte leukemia
  • 1-ethyl-1-nitrosourea (ENU)
Leukocyte

21

C57L/J Leukocyte leukemia Leukocyte

1.3

SWR/J Leukocyte leukemia
  • 1-ethyl-1-nitrosourea (ENU)
Leukocyte

17

SWR/J Leukocyte leukemia Leukocyte

7.3

C57BL/6J Leukocyte leukemia
  • 1-ethyl-1-nitrosourea (ENU)
Leukocyte

20

C57BL/6J Leukocyte leukemia Leukocyte

2.7

DBA/2J Leukocyte leukemia
  • 1-ethyl-1-nitrosourea (ENU)
Leukocyte

44

DBA/2J Leukocyte leukemia Leukocyte

11

AKR/J Leukocyte leukemia
  • 1-ethyl-1-nitrosourea (ENU)
Leukocyte

44

AKR/J Leukocyte leukemia Leukocyte

74

DBA/2J Liver hepatoma Liver

observed

C57L/J Liver tumor
  • 1-ethyl-1-nitrosourea (ENU)
Liver

2.7

DBA/2J Liver tumor
  • 1-ethyl-1-nitrosourea (ENU)
Liver

3.4

C57L/J Lung adenoma
  • 1-ethyl-1-nitrosourea (ENU)
Lung

6.7

C57L/J Lung adenoma Lung

0

SWR/J Lung adenoma
  • 1-ethyl-1-nitrosourea (ENU)
Lung

40

SWR/J Lung adenoma Lung

11

C57BL/6J Lung adenoma
  • 1-ethyl-1-nitrosourea (ENU)
Lung

7.1

C57BL/6J Lung adenoma Lung

0

DBA/2J Lung adenoma
  • 1-ethyl-1-nitrosourea (ENU)
Lung

2.3

DBA/2J Lung adenoma Lung

0

AKR/J Lung adenoma
  • 1-ethyl-1-nitrosourea (ENU)
Lung

14

AKR/J Lung adenoma Lung

0

SWR/J Mammary gland tumor
  • 1-ethyl-1-nitrosourea (ENU)
Mammary gland

0.9

DBA/2J Mammary gland tumor Mammary gland

1.1

C57L/J Ovary tumor
  • 1-ethyl-1-nitrosourea (ENU)
Ovary

2.7

SWR/J Ovary tumor
  • 1-ethyl-1-nitrosourea (ENU)
Ovary

2.8

C57L/J (Unspecified organ) tumor
  • 1-ethyl-1-nitrosourea (ENU)
(Unspecified organ)

5.3

SWR/J (Unspecified organ) tumor
  • 1-ethyl-1-nitrosourea (ENU)
(Unspecified organ)

1.8 - 2.8

SWR/J (Unspecified organ) tumor (Unspecified organ)

1.0

C57BL/6J (Unspecified organ) tumor
  • 1-ethyl-1-nitrosourea (ENU)
(Unspecified organ)

2.4

DBA/2J (Unspecified organ) tumor
  • 1-ethyl-1-nitrosourea (ENU)
(Unspecified organ)

3.4