Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-05-26
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
A/J
Strain Synonyms A  •  A/Cloudman  •  AJ  •  A/Jax  •  A/J, H-2a  •  A/J-Jax  •  A/Lilly  •  strain A  •  Strain A
Strain Tumor Overview Expanded View
Tumors 212 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous) 2 0
Adipose tissue lipoma Peritoneal cavity None (spontaneous) 2 0
Adipose tissue lipoma - pedunculated Peritoneum - Mesentery None (spontaneous) 1 observed
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous) 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 2 0
Adrenal gland - Cortex hyperplasia - nodular Adrenal gland - Cortex None (spontaneous) 1 observed
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Cortex None (spontaneous) 2 20 - 60
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous) 2 0 - moderate
Adrenal gland hyperplasia Adrenal gland None (spontaneous) 2 observed
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous) 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous) 4 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous) 2 0
Blood vessel hemangioma Blood vessel None (spontaneous) 2 0
Blood vessel hemangioma Uterus None (spontaneous) 1 0
Blood vessel hemangioma - capillary Muscle - Striated - Skeletal None (spontaneous) 1 observed
Blood vessel hemangioma - cavernous Blood vessel None (spontaneous) 2 observed
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0
Blood vessel hemangiosarcoma Liver None (spontaneous) 2 0
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Bone hyperplasia Bone None (spontaneous) 3 0 - observed
Bone lesion - fibro-osseous Bone None (spontaneous) 11 0
Epididymis cyst Epididymis None (spontaneous) 1 0
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous) 2 0
Erythrocyte neoplasm Erythrocyte None (spontaneous) 2 0
Esophagus hyperplasia Esophagus None (spontaneous) 2 0
Eye - Harderian gland adenoma Eye - Harderian gland None (spontaneous) 1 observed
Eye - Lacrimal gland hyperplasia Eye - Lacrimal gland None (spontaneous) 1 observed
Forestomach carcinoma in situ Forestomach Chemical/Drug 2 observed
Forestomach hyperplasia Forestomach Chemical/Drug 2 observed
Forestomach hyperplasia Forestomach None (spontaneous) 1 observed
Forestomach hyperplasia - papillary Forestomach None (spontaneous) 3 0 - observed
Forestomach papilloma Forestomach Chemical/Drug 16 observed - 100
Forestomach papilloma Forestomach None (spontaneous) 3 0
Forestomach papilloma Forestomach Diet 1 observed
Forestomach squamous cell carcinoma Forestomach Chemical/Drug 2 observed
Forestomach tumor Forestomach None (spontaneous) 2 0
Forestomach tumor Forestomach Diet 3 0 - 87
Forestomach tumor Forestomach Chemical/Drug 10 72 - 100
Gallbladder cyst Gallbladder None (spontaneous) 4 0 - moderate
Gallbladder hyperplasia Gallbladder None (spontaneous) 3 0 - observed
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous) 2 0
Gastrointestinal tract carcinoma Gastrointestinal tract Chemical/Drug 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous) 3 0 - moderate
Intestine - Large Intestine - Colon - Distal adenocarcinoma Intestine - Large Intestine - Colon - Distal Chemical/Drug 1 observed
Intestine - Large Intestine - Colon - Distal adenoma - polypoid Intestine - Large Intestine - Colon - Distal Chemical/Drug 1 observed
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal Chemical/Drug 2 observed
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Distal squamous cell carcinoma Intestine - Large Intestine - Colon - Distal Chemical/Drug 1 observed
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal Chemical/Drug 2 observed - 100
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal Chemical/Drug 2 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal None (spontaneous) 1 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 2 0
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug 2 observed - 100
Intestine - Large Intestine tumor Intestine - Large Intestine Chemical/Drug 1 100
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum adenocarcinoma in situ Intestine - Small Intestine - Duodenum None (spontaneous) 1 observed
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine normal tissue (control) Intestine - Small Intestine None (spontaneous) 1 not applicable
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine Chemical/Drug 1 0
Kidney - Renal tubule adenoma Kidney - Renal tubule None (spontaneous) 1 observed
Kidney adenoma Kidney None (spontaneous) 4 0 - low
Kidney tumor Kidney None (spontaneous) 1 0
Kidney tumor Kidney Chemical/Drug 1 0
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous) 2 0
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous) 4 1
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lung None (spontaneous) 1 1
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous) 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug 1 0
Leukocyte leukemia Leukocyte None (spontaneous) 2 1.6 - 3.1
Leukocyte leukemia Leukocyte Virus 2 70 - 82
Leukocyte lymphoma Leukocyte None (spontaneous) 3 0 - 1
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous) 2 0
Liver hepatoma Liver None (spontaneous) 3 0 - 1
Liver tumor Liver None (spontaneous) 1 0
Liver tumor Liver Chemical/Drug 1 0
Lung - Alveolus adenoma Lung - Alveolus None (spontaneous) 11 0 - 51
Lung - Alveolus adenoma Lung - Alveolus Diet 1 0
Lung - Alveolus adenoma Lung - Alveolus Chemical/Drug 35 observed - 100
Lung - Alveolus carcinoma Lung - Alveolus Chemical/Drug 2 observed
Lung - Alveolus hyperplasia Lung - Alveolus Chemical/Drug 6 observed
Lung - Alveolus lesion Lung - Alveolus None (spontaneous) 4 0 - 50
Lung - Alveolus lesion Lung - Alveolus Chemical/Drug 6 100
Lung - Bronchiole adenoma Lung - Bronchiole Chemical/Drug 1 observed
Lung - Bronchiole hyperplasia Lung - Bronchiole Chemical/Drug 2 observed
Lung - Club cell carcinoma Lung - Club cell Radiation 1 11
Lung adenocarcinoma Lung Chemical/Drug 11 0 - very high
Lung adenocarcinoma Lung None (spontaneous) 1 0
Lung adenocarcinoma - mixed Lung Chemical/Drug 1 observed
Lung adenocarcinoma - papillary Lung Chemical/Drug 1 observed
Lung adenocarcinoma - solid Lung Chemical/Drug 1 observed
Lung adenoma Lung Chemical/Drug 194 0 - 100
Lung adenoma Lung None (spontaneous) 53 0 - 80
Lung adenoma Lung Radiation 3 observed - 55
Lung adenoma Lung Diet 45 0 - 100
Lung adenoma Lung Hormone 1 observed
Lung carcinoma Lung None (spontaneous) 5 0 - 11.11
Lung carcinoma Lung Radiation 2 observed
Lung carcinoma Lung Chemical/Drug 36 0 - 86
Lung dysplasia Lung Chemical/Drug 1 59
Lung dysplasia Lung Diet 1 69
Lung hyperplasia Lung Radiation 3 observed - 10
Lung hyperplasia Lung None (spontaneous) 5 0 - observed
Lung hyperplasia Lung Chemical/Drug 37 0 - very high
Lung metaplasia - squamous Lung Chemical/Drug 1 very high
Lung normal tissue (control) Lung Chemical/Drug 2 not applicable
Lung papilloma Lung None (spontaneous) 1 0
Lung papilloma Lung Chemical/Drug 1 0
Lung squamous cell carcinoma Lung None (spontaneous) 1 0
Lung squamous cell carcinoma Lung Chemical/Drug 2 48 - 50
Lung tumor Lung None (spontaneous) 79 0 - 100
Lung tumor Lung Chemical/Drug 244 observed - 100
Lung tumor Lung Radiation 4 0 - 72
Lung tumor Lung Diet 1 79
Lymph node cyst Lymph node None (spontaneous) 3 0 - moderate
Lymph node hyperplasia Reticulocyte None (spontaneous) 2 0
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 7 0 - 28
Mammary gland tumor Mammary gland None (spontaneous) 6 1 - moderate
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous) 1 0
Mesothelium mesothelioma Peritoneal cavity None (spontaneous) 1 observed
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous) 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous) 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0
Muscle - Striated - Skeletal lesion Muscle - Striated - Skeletal None (spontaneous) 1 observed
Muscle - Striated - Skeletal neoplasm Muscle - Striated - Skeletal None (spontaneous) 1 observed
Muscle - Striated - Skeletal normal tissue (control) Muscle - Striated - Skeletal None (spontaneous) 1 not applicable
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 15 0 - low
Muscle - Striated - Skeletal rhabdomyosarcoma CNS - Spinal cord None (spontaneous) 1 observed
Muscle - Striated - Skeletal rhabdomyosarcoma Leg None (spontaneous) 1 observed
Muscle - Striated - Skeletal rhabdomyosarcoma Bone - Vertebral column None (spontaneous) 1 observed
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous) 18 0 - 78.95
Muscle - Striated - Skeletal rhabdomyosarcoma - well differentiated Muscle - Striated - Skeletal None (spontaneous) 1 observed
Muscle - Striated - Skeletal tumor Muscle - Striated - Skeletal None (spontaneous) 1 observed
Myoepithelial cell myoepithelioma Myoepithelial cell None (spontaneous) 3 1
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous) 4 0 - observed
Myoepithelial cell myoepithelioma Blood vessel None (spontaneous) 1 observed
Myoepithelial cell myoepithelioma Lung None (spontaneous) 2 0
Nail squamous cell carcinoma Nail None (spontaneous) 2 0
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous) 1 0
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous) 2 1
Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell None (spontaneous) 1 0
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous) 1 0
Ovary adenoma Ovary None (spontaneous) 1 0
Ovary cyst Ovary None (spontaneous) 3 observed
Ovary cyst - bursal Ovary None (spontaneous) 1 0
Ovary hyperplasia - epithelial Ovary None (spontaneous) 1 0
Ovary tumor - tubulostromal Ovary None (spontaneous) 1 0
PNS - Nerve sheath tumor Ear None (spontaneous) 2 0
PNS - Nerve sheath tumor Skin None (spontaneous) 2 0
PNS - Nerve sheath tumor - malignant Subcutis None (spontaneous) 1 observed
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous) 2 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous) 4 observed
Pancreas carcinoma in situ Pancreas None (spontaneous) 1 observed
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous) 1 0
Salivary gland carcinoma Salivary gland None (spontaneous) 1 1
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous) 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous) 2 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous) 2 0
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous) 2 0
Skin hyperplasia - epithelial Ear None (spontaneous) 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous) 2 0
Skin tumor Skin Chemical/Drug 1 64
Spleen hyperplasia Spleen None (spontaneous) 3 observed
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous) 3 0 - observed
Stomach - Glandular cyst Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular polyp Stomach - Glandular None (spontaneous) 2 0
Stomach papilloma Stomach None (spontaneous) 2 observed - low
Stomach papilloma Stomach Chemical/Drug 4 low
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Thymus thymoma Thymus None (spontaneous) 1 1
Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell None (spontaneous) 3 observed
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous) 2 0
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous) 2 0
Ureter hyperplasia Muscle - Smooth None (spontaneous) 2 0
Ureter polyp Ureter None (spontaneous) 2 0
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous) 2 0
Urinary bladder papilloma Urinary bladder Chemical/Drug 1 1
Urinary bladder papilloma Urinary bladder None (spontaneous) 2 0
Uterus - Cervix squamous cell carcinoma Uterus - Cervix None (spontaneous) 1 observed
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous) 6 observed - moderate
Uterus adenoma Uterus None (spontaneous) 1 0
Uterus fibropapilloma Uterus None (spontaneous) 1 0
Vagina papilloma Vagina None (spontaneous) 1 0
Vulva squamous cell carcinoma Vulva None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 2 13 - 30
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=4
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/A.shtml
JAX Mice http://jaxmice.jax.org/strain/000646.html