Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-05-26
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
C57BL/6
Strain Synonyms B6  •  B6 wild-type  •  C57  •  C57/B16  •  C57B1/6  •  C57BL  •  C57Bl6  •  C57BL6  •  C57BL/6 wild-type  •  C57BL/6 WT  •  p53+/+  •  pure C57BL/6  •  wild-type  •  wild type C57BL/6  •  WT
Strain Note: Substrain not specified.
Strain Tumor Overview Expanded View
Tumors 66 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Cortex None (spontaneous) 2 0 - 87
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 observed
CNS - Brain - Astrocyte astrocytoma CNS - Brain - Astrocyte None (spontaneous) 2 0
CNS - Brain glioma CNS - Brain Genetic Modification 1 observed
CNS - Brain tumor CNS - Brain Virus 2 0 - 43
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous) 1 0
Esophagus tumor Esophagus None (spontaneous) 1 0
Esophagus tumor Esophagus Chemical/Drug 3 0
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon Chemical/Drug 1 observed
Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum Chemical/Drug 3 42 - 67
Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum None (spontaneous) 1 0
Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum Chemical/Drug 1 0
Intestine adenoma Intestine None (spontaneous) 1 0
Intestine adenoma Intestine Chemical/Drug 2 0
Kidney adenocarcinoma Kidney None (spontaneous) 1 0
Kidney cyst Kidney None (spontaneous) 1 5.56
Leukocyte - Lymphocyte leukemia Lymphoid tissue None (spontaneous) 1 observed
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous) 1 2
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 10 - 22
Leukocyte leukemia Leukocyte None (spontaneous) 2 7.0 - 16.0
Leukocyte lymphoma Leukocyte Virus 5 0 - 80
Leukocyte lymphoma Leukocyte Chemical/Drug 2 high - 100
Leukocyte lymphoma Leukocyte None (spontaneous) 1 5.56
Liver adenoma Liver Chemical/Drug 7 0 - 88.89
Liver hepatocellular carcinoma Liver None (spontaneous) 1 0
Liver hepatocellular carcinoma Liver Radiation 1 11.11
Liver hepatoma Liver Radiation 1 high
Liver hepatoma Liver None (spontaneous) 1 11.11
Liver preneoplastic lesion Liver Chemical/Drug 1 observed
Lung adenocarcinoma Lung Chemical/Drug 3 observed - 42
Lung adenocarcinoma Lung None (spontaneous) 1 0
Lung adenoma Lung Chemical/Drug 3 0 - 10
Lung adenoma Lung None (spontaneous) 3 0 - 5.56
Lung carcinoma Lung Chemical/Drug 1 0
Lung carcinoma Lung None (spontaneous) 1 0
Lung hyperplasia Lung Chemical/Drug 2 observed
Lung hyperplasia Lung None (spontaneous) 1 observed
Lung papilloma Lung None (spontaneous) 1 0
Lung papilloma Lung Chemical/Drug 1 0
Lung squamous cell carcinoma Lung None (spontaneous) 1 0
Lung squamous cell carcinoma Lung Chemical/Drug 1 23
Lung tumor Lung None (spontaneous) 7 0 - 4.4
Lung tumor Lung Chemical/Drug 9 0 - 46
Lung tumor Lung Genetic Modification 2 0 - 50
Lymphoid tissue lymphoma Lymphoid tissue None (spontaneous) 1 0
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 1 1
Mammary gland normal tissue (control) Mammary gland None (spontaneous) 1 not applicable
Mammary gland tumor Mammary gland None (spontaneous) 2 very low - low
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast Chemical/Drug 1 observed
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 observed
Ovary tumor Ovary Genetic Modification 1 0
Pituitary gland tumor Pituitary gland None (spontaneous) 3 observed - 61
Prostate gland normal tissue (control) Prostate gland None (spontaneous) 1 not applicable
Prostate gland tumor Prostate gland Hormone 1 0
Seminal vesicle normal tissue (control) Seminal vesicle None (spontaneous) 1 not applicable
Skin carcinoma Skin Chemical/Drug 1 0
Skin papilloma Skin Chemical/Drug 1 observed
Stomach tumor Stomach None (spontaneous) 1 0
Stomach tumor Stomach Chemical/Drug 3 0
Thymus normal tissue (control) Thymus None (spontaneous) 1 not applicable
Thymus thymoma Thymus Virus 1 high
Urinary bladder dysplasia Urinary bladder Chemical/Drug 1 50
Urinary bladder hyperplasia Urinary bladder Chemical/Drug 1 observed
Urinary bladder squamous cell carcinoma Urinary bladder Chemical/Drug 1 0
Urinary bladder transitional cell carcinoma Urinary bladder Chemical/Drug 1 20
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 3 0 - low
Other Database Links
Additional information about these mice:
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/C57BL.shtml