Strain SummaryC3HeB/FeJ

Strain Name

C3HeB/FeJ

Strain Type(s)

embryo transfer  •  inbred

Strain Synonym(s)

C3Fe  •  C3H  •  C3HeB/FeJ MMTV-  •  C3HeB/FeJ-MTV-  •  C3HFe  •  C3H Fekete  •  C3H/HeBFeJ  •  C3H/HeBFeJ mtv-  •  C3HeB/FeJax  •  C3He/JFe  •  HeB  •  MTV-  •  TC3H

Description

C3H embryo transferred to C57BL/6. These mice do not carry MMTV.

Strain Links

• Mouse Phenome Database (MPD)
• Festing's List of Inbred Strains
• JAX Mice

Models

89 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Bone - Skull osteosarcoma Bone - Skull diethylstilbestrol (DES)   ⋅   corn oil

observed - 2.7

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Bone hyperplasia Bone corn oil

0

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Bone hyperplasia Bone diethylstilbestrol (DES)   ⋅   corn oil

5.56 - 97.3

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Bone osteosarcoma Bone corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Bone osteosarcoma Bone diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Eye - Harderian gland adenocarcinoma Eye - Harderian gland

1.0

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Eye - Harderian gland adenoma - acinar Eye - Harderian gland

0.5

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Eye - Harderian gland adenoma - cystic Eye - Harderian gland

0.5

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Eye - Harderian gland adenoma - cystic papillary Eye - Harderian gland

1.0

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Eye - Harderian gland adenoma - papillary Eye - Harderian gland

2.0

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Eye - Harderian gland tumor Eye - Harderian gland

5.1

References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8

Leukocyte leukemia Leukocyte

0 - 6.9

References: Myers DD, Life Sci 1970;9(Pt II):1071-80

Liver hepatocellular adenoma Liver MMTV - mouse mammary tumor virus   ⋅   corn oil

1.45

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Liver hepatocellular adenoma Liver MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

2.13

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Liver hepatocellular carcinoma Liver MMTV - mouse mammary tumor virus   ⋅   corn oil

10.14

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Liver hepatocellular carcinoma Liver MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

5.33

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Liver hepatoma Liver

observed - 31

References: Staats J, Companion to Mouse News Lett No. 29 1963;():   ⋅   Storer JB, J Gerontol 1966 Jul;21(3):404-9

Liver tumor Liver

observed

References: Storer JB, J Gerontol 1966 Jul;21(3):404-9

Mammary gland adenocarcinoma Mammary gland corn oil

0 - 51.28

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mammary gland adenocarcinoma Mammary gland diethylstilbestrol (DES)   ⋅   corn oil

0 - 60

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mammary gland adenocarcinoma - acinar Mammary gland

observed

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Mammary gland adenocarcinoma - type B Mammary gland

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Mammary gland carcinoma Mammary gland corn oil

8.11

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mammary gland hyperplasia - alveolar Mammary gland

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Mammary gland hyperplasia - alveolar Mammary gland corn oil

0 - 5.41

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mammary gland hyperplasia - alveolar Mammary gland diethylstilbestrol (DES)   ⋅   corn oil

0 - 70

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mammary gland tumor Mammary gland

observed

low

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Storer JB, J Gerontol 1966 Jul;21(3):404-9

Mammary gland tumor Mammary gland MMTV - mouse mammary tumor virus

high

References: Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():

Mammary gland tumor Mammary gland corn oil

0

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Mammary gland tumor Mammary gland diethylstilbestrol (DES)   ⋅   corn oil

0

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Mesothelium mesothelioma Uterus corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Mesothelium mesothelioma Uterus diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary - Germ cell teratoma Ovary - Germ cell corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary - Germ cell teratoma Ovary - Germ cell diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary - Granulosa cell tumor Ovary - Granulosa cell corn oil

5.3

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary adenoma - tubular Ovary corn oil

0 - 36.36

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary adenoma - tubular Ovary diethylstilbestrol (DES)   ⋅   corn oil

0 - 50

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary luteoma Ovary corn oil

2.1

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Ovary tumor Ovary

22 - 64

References: Murphy ED, 1966;():521-62   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 25 1961;():

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Pituitary gland adenoma Pituitary gland corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Pituitary gland adenoma Pituitary gland diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

observed

References: Sundberg J, Personal Communication 1997;():

5 pathology image(s)

Skin squamous cell carcinoma Skin corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Skin squamous cell carcinoma Skin diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Thyroid gland carcinoma Thyroid gland corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Thyroid gland carcinoma Thyroid gland diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Uterus - Cervix corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Uterus - Cervix diethylstilbestrol (DES)   ⋅   corn oil

observed - 5.56

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Uterus - Cervix 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Urinary bladder 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Urethra 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Ureter 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Vagina 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Intestine - Large Intestine - Rectum 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix adenocarcinoma Uterus 17beta-estradiol (E2)   ⋅   MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix hyperplasia Uterus - Cervix 17beta-estradiol (E2)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Cervix lesion Uterus - Cervix corn oil

0 - 14.29

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix lesion Uterus - Cervix diethylstilbestrol (DES)   ⋅   corn oil

0 - 100

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix lesion Uterus - Cervix 17beta-estradiol (E2)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Cervix myoblastoma - granular cell Uterus - Cervix corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix myoblastoma - granular cell Uterus - Cervix diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix squamous cell carcinoma Uterus - Cervix corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Cervix squamous cell carcinoma Uterus - Cervix diethylstilbestrol (DES)   ⋅   corn oil

0 - observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Endometrium carcinoma Uterus - Endometrium corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Endometrium carcinoma Uterus - Endometrium MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Endometrium hyperplasia Uterus - Endometrium 17beta-estradiol (E2)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Endometrium polyp Uterus - Endometrium corn oil

1.47

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Endometrium polyp Uterus - Endometrium MMTV - mouse mammary tumor virus   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

5.25

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Uterine horn adenoacanthoma Uterus - Uterine horn corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Uterine horn adenoacanthoma Uterus - Uterine horn diethylstilbestrol (DES)   ⋅   corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Uterine horn adenocarcinoma Uterus - Uterine horn corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Uterine horn adenocarcinoma Uterus - Uterine horn diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus - Uterine horn hyperplasia - glandular Uterus - Uterine horn corn oil

11.11

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Uterine horn hyperplasia - glandular Uterus - Uterine horn diethylstilbestrol (DES)   ⋅   corn oil

5.13 - 94.59

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Uterine horn lesion Uterus - Uterine horn corn oil

16.67

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus - Uterine horn lesion Uterus - Uterine horn diethylstilbestrol (DES)   ⋅   corn oil

5.13 - 86.49

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30

Uterus adenocarcinoma Uterus corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus adenocarcinoma Uterus diethylstilbestrol (DES)   ⋅   corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus atypia Uterus 17beta-estradiol (E2)   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Uterus hyperplasia - glandular Uterus

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Uterus preneoplastic lesion Uterus 17beta-estradiol (E2)   ⋅   diethylstilbestrol (DES)   ⋅   corn oil

observed

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Vagina squamous cell carcinoma Vagina corn oil

0

References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

Vagina squamous cell carcinoma Vagina diethylstilbestrol (DES)   ⋅   corn oil

observed - 2.7

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30   ⋅   Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95

(Unspecified organ) tumor (Unspecified organ)

55

31

References: Storer JB, J Gerontol 1966 Jul;21(3):404-9

(Unspecified organ) tumor - malignant (Unspecified organ) corn oil

0

References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30