Strain SummaryC3Bir.129P2(B6)-Il10tm1Cgn/LtJ

Strain Name

C3Bir.129P2(B6)-Il10tm1Cgn/LtJ

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

C3Bir.129P2(B6)-Il10tm1Cgn  •  C3Bir.129P2(B6)-Il10tm1Cgn/J  •  C3Bir.129P2-Il10tm1Cgn/LtJ  •  C3H-Il10-/-  •  IL-10-/-

Description

Homozygous mice. These mice were generated using E14-1 (129P2/OlaHsd) ES cells. They were initially bred with C57BL/6J mice and later backcrossed to C3H/HeJBir mice.

Strain Links

• JAX Mice

Strain Genetics

Il10tm1Cgn / Il10tm1Cgn

Models

7 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Cecum hyperplasia - epithelial Intestine - Large Intestine - Cecum

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Intestine - Large Intestine - Colon - Distal hyperplasia - epithelial Intestine - Large Intestine - Colon - Distal

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Intestine - Large Intestine - Colon - Medial hyperplasia - epithelial Intestine - Large Intestine - Colon - Medial

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Intestine - Large Intestine - Colon - Proximal hyperplasia - epithelial Intestine - Large Intestine - Colon - Proximal

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Intestine - Large Intestine - Colon hyperplasia - epithelial Intestine - Large Intestine - Colon

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Intestine lesion Intestine

observed

References: Bleich A, Mamm Genome 2004 Nov;15(11):865-71

Mammary gland adenocarcinoma - papillary Mammary gland

observed

References: Mikaelian I, Personal Communication 2004;():

2 pathology image(s)