Strain SummaryB6.Cg-Lep^ob/J

Strain Name	B6.Cg-Lep^ob/J
Strain Type(s)	congenic • spontaneous mutation
Strain Synonym(s)	B6 ob • B6.V-Lep^ob • B6.V-Lep^ob/J • B6.V-LepJ/+ • B6.V-Lep^ob • C57BL/6J-Lep^ob • C57BL/6J-Lep^ob • lean • lean litter mates
Description	Heterozygous mice - "obese" mutation. The genetic background of these mice is C57BL/6J.
Strain Links	• JAX Mice
Strain Genetics	List all models in MMHCdb carrying the Lep^ob allele Lep^ob / Lep⁺

Models
7 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Ear - Outer ear adenoma - sebaceous	Ear - Outer ear			observed			References: Sundberg J, Personal Communication 1997;(): 3 pathology image(s)
Ear - Outer ear papilloma	Ear - Outer ear			observed			References: Sundberg J, Personal Communication 1997;():
Liver hyperplasia	Liver					0	References: Yang S, Cancer Res 2001 Jul 1;61(13):5016-23
Skin carcinoma	Skin		observed				References: Sundberg J, Personal Communication 1997;():
Skin neoplasm	Skin		observed				References: Sundberg J, Personal Communication 1997;():
Skin papilloma	Skin		observed				References: Sundberg J, Personal Communication 1997;():
Skin squamous cell carcinoma - well differentiated	Skin		observed				References: Sundberg J, Personal Communication 1997;(): 6 pathology image(s)

Models