Strain SummaryFVB/N-Tg(MMTV-PyVT)634Mul

Strain Name

 FVB/N-Tg(MMTV-PyVT)634Mul

Strain Type(s)

 transgenic

Strain Synonym(s)

 634 line  •  E2FWT/WT  •  FVB/N-Tg(MMTVPyVT)634Mul  •  FVB/N-TgN(MMTVPyVT)634Mul  •  FVB/N-TgN(MMTVPyVT)634Mul  •  -PyMT  •  PyMT  •  MMTV-PymT  •  MMTV-PyMT  •  MMTV/middle T  •  MMTV/middle T antigen  •  MMTV-PyMT  •  MMTV-PyMT634  •  MMTV-PyMT E2FWT/WT  •  MMTV-PyV middle T antigen  •  MMTV/PyV middle T antigen  •  MMTV/PyV MT  •  MT#634  •  MT No. 634  •  polyoma middle T antigen  •  PyMT  •  PyMT (control)

Description

 Transgenic mice. The genetic background of these mice was FVB/N.

Strain Genetics

 Tg(MMTV-PyVT)634Mul

Models

12 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland adenocarcinoma Mammary gland

observed - 100

100

References: Guy CT, Genes Dev 1994 Jan;8(1):23-32   ⋅   Guy CT, Mol Cell Biol 1992 Mar;12(3):954-61   ⋅   Trimble MS, Oncogene 1993 Nov;8(11):3037-42

Sites of Metastasis: Lung
Mammary gland hyperplasia Mammary gland

observed

References: White DE, Cancer Cell 2004 Aug;6(2):159-70

Mammary gland tumor Mammary gland

observed

observed - 100

References: Hodgson JG, Cancer Res 2005 Nov 1;65(21):9695-704   ⋅   Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43   ⋅   Lancaster M, Mamm Genome 2005 Feb;16(2):120-6   ⋅   Lifsted T, Int J Cancer 1998 Aug 12;77(4):640-4   ⋅   White DE, Cancer Cell 2004 Aug;6(2):159-70

Sites of Metastasis: Lung
Mammary gland tumor - adenosquamous Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - glandular Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - luminal Mammary gland

observed

References: Zhu M, Genome Biol 2011;12(8):R77

Mammary gland tumor - microacinar Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - microacinar/adenosquamous Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - mixed Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - papillary Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Mammary gland tumor - solid Mammary gland

observed

References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

(Unspecified organ) tumor (Unspecified organ)

observed

References: Lancaster M, Mamm Genome 2005 Feb;16(2):120-6