Strain SummaryNZO/HlLtJ

Strain Name

NZO/HlLtJ

Strain Type(s)

inbred

Strain Synonym(s)

New Zealand Obese  •  NZO/H1LtJ  •  NZO/HiLtJ  •  NZO/HlLtJ-PctpR120H

Description

Strain was derived from crossing NON/Lt and NZO/Hl and contains the PctpR120H allele.

Strain Links

• JAX Mice

Strain Genetics

PctpR120H / PctpR120H

Models

122 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue - White lipoma Adipose tissue - White

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma - pedunculated Adipose tissue

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell

high

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - nodular Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - spindle cell Adrenal gland

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland tumor - carcinoid Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Blood vessel hemangioma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Liver

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone - Femur hyperplasia Bone - Femur

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Bone hyperplasia Bone

0 - observed

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone lesion - fibro-osseous Bone

8.33 - 33.33

0

5.88 - 18.18

References: Berndt A, Exp Mol Pathol 2015 Nov 14;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone marrow hyperplasia Bone marrow

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Epididymis cyst Epididymis

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte leukemia - erythroleukemia Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte neoplasm Erythrocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Esophagus hyperplasia Esophagus

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Eye - Harderian gland hyperplasia Eye - Harderian gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Eye - Lacrimal gland hyperplasia Eye - Lacrimal gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Forestomach hyperplasia - papillary Forestomach

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach papilloma Forestomach

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder cyst Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia - papillary Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland

0

observed - moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Kidney adenoma Kidney

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell neoplasm Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte lymphoma Leukocyte

low

observed - moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct adenoma Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct hyperplasia Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver hepatoma Liver

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lung adenoma Lung

observed - 33.33

observed - 40

References: Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

8 pathology image(s)

Lung hyperplasia Lung

0

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node - Cervical cyst Lymph node - Cervical

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Lymph node - Mesenteric cyst Lymph node - Mesenteric

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Lymph node cyst Lymph node

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node hyperplasia Reticulocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mammary gland cyst Mammary gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Seminal vesicle

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mouth - Oral mucosa cyst Mouth - Oral mucosa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyoma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal

0

References: Sher RB, PLoS One 2011;6(8):e23498

Myoepithelial cell myoepithelioma Lung

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Myoepithelial cell myoepithelioma Mammary gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Nail squamous cell carcinoma Nail

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Follicle cyst - follicular Ovary - Follicle

very high

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Luteal cell tumor Ovary - Luteal cell

observed - high

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Sex cord stromal cell adenoma - tubulostromal Ovary - Sex cord stromal cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Ovary adenoma Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cyst Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Ovary cyst - bursal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary hyperplasia - epithelial Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary tumor - tubulostromal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Duct adenoma Pancreas - Duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Pancreas - Islet of Langerhans cyst Pancreas - Islet of Langerhans

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

2 pathology image(s)

Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis cyst - epidermoid Tail

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Skin - Epidermis cyst - inclusion Skin - Epidermis

low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular adenoma Stomach - Glandular

0

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst - glandular Stomach - Glandular

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia Stomach - Glandular

observed - moderate

moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular

moderate

moderate

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular polyp Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Thyroid gland cyst Thyroid gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Thyroid gland hyperplasia - cystic Thyroid gland

moderate

observed - high

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter - Transitional cell hyperplasia Ureter - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter hyperplasia Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter polyp Ureter

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder papilloma Urinary bladder

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium

observed - low

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus adenoma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus fibropapilloma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vagina papilloma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vulva squamous cell carcinoma Vulva

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():