Strain Summary129S-Atmtm1Awb Rag2tm1Fwa
Strain Name |
129S-Atmtm1Awb Rag2tm1Fwa |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Rag2-/- Atm-/- |
Description |
Homozygous mutants were maintained on a 129S background that included contributions from at least 129S6/SvEvTac and 129S/SvEv-Gpi1c. |
Strain Genetics |
Rag2tm1Fwa / Rag2tm1Fwa |
Atmtm1Awb / Atmtm1Awb |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte lymphoma | Thymus |
25 |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 5 cytogenetic image(s) |
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Leukocyte lymphoma - disseminated | Leukocyte |
29.17 |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
observed |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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Ovary - Granulosa cell tumor | Ovary - Granulosa cell |
observed |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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(Unspecified organ) tumor | (Unspecified organ) |
29.17 |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |