Strain Summary129S-Atmtm1Awb Rag2tm1Fwa

Strain Name

129S-Atmtm1Awb Rag2tm1Fwa

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Rag2-/- Atm-/-

Description

Homozygous mutants were maintained on a 129S background that included contributions from at least 129S6/SvEvTac and 129S/SvEv-Gpi1c.

Strain Genetics

Rag2tm1Fwa / Rag2tm1Fwa
Atmtm1Awb / Atmtm1Awb

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Thymus

25

References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9

5 cytogenetic image(s)

Leukocyte lymphoma - disseminated Leukocyte

29.17

References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9

Ovary - Granulosa cell tumor Ovary - Granulosa cell

observed

References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9

(Unspecified organ) tumor (Unspecified organ)

29.17

References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9