Strain SummaryB6.Cg-Lepob/J
Strain Name |
B6.Cg-Lepob/J |
Strain Type(s) |
congenic • spontaneous mutation |
Strain Synonym(s) |
B6 ob • B6.V-Lepob • B6.V-Lepob/J • C57BL/6J-Lepob • ob/ob • ob/ob C57BL-6J • obese |
Description |
Homozygous mice - "obese" mutation. The genetic background of these mice is C57BL/6J. |
Strain Links |
• JAX Mice |
Strain Genetics |
Lepob / Lepob |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Blood vessel hemangiosarcoma | Subcutis |
observed |
References: Mikaelian I, Personal Communication 2004;(): 10 pathology image(s) |
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Clitoral gland adenoma | Clitoral gland |
observed |
References: Sundberg J, Personal Communication 1997;(): 5 pathology image(s) |
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Liver hyperplasia | Liver |
observed |
References: Yang S, Cancer Res 2001 Jul 1;61(13):5016-23 |
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Skin gland - Sebaceous gland adenoma - sebaceous | Ear |
observed |
References: Sundberg J, Personal Communication 1997;(): 3 pathology image(s) |
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Skin gland - Sebaceous gland papilloma - sebaceous | Ear |
observed |
References: Sundberg J, Personal Communication 1997;(): 3 pathology image(s) |