Strain SummaryFVB.129S7-Trp53tm1Brd
Strain Name |
FVB.129S7-Trp53tm1Brd |
Strain Type(s) |
congenic • targeted mutation (knockout) |
Strain Synonym(s) |
p53-/- |
Description |
Homozygous mice. These mice had been backcrossed to FVB. The mutation was generated in a 129S7/SvEvBrd-Hprt+ genetic background. |
Strain Genetics |
Trp53tm1Brd / Trp53tm1Brd |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte - Lymphocyte lymphoma | Leukocyte - Lymphocyte | MuLV - murine leukemia virus (MLV) |
observed |
References: Mattison J, Cancer Res 2010 Feb 1;70(3):883-95 |