Strain SummaryFVB.129-Cdkn1atm1Led Cdkn2btm1Brn

Strain Name

FVB.129-Cdkn1atm1Led Cdkn2btm1Brn

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

p15-/-, p21-/-

Description

Homozygous mice. These mice had been backcrossed to FVB. The mutations were generated in a genetic background that included 129S6/SvEvTac and 129P2/OlaHsd.

Strain Genetics

Cdkn1atm1Led / Cdkn1atm1Led
Cdkn2btm1Brn / Cdkn2btm1Brn

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte MuLV - murine leukemia virus (MLV)

observed

References: Mattison J, Cancer Res 2010 Feb 1;70(3):883-95