Strain SummaryFVB-Tg(C3-1-TAg)cJeg
Strain Name |
FVB-Tg(C3-1-TAg)cJeg |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
C3(1)-Tag • C3(1)/Tag • C3-TAg • FVB_C3(1)_Tag • FVB_C3(1)-Tag • FVB_C3Tag • C3-TAg • TgC3(1)-Tag • Tg(C3-1-TAg)cJeg |
Description |
The genetic background of these mice was FVB (substrain not specified). |
Strain Genetics |
Tg(C3-1-TAg)cJeg |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Mammary gland carcinoma | Mammary gland |
observed |
observed |
References: Herschkowitz JI, Genome Biol 2007;8(5):R76 ⋅ Pfefferle AD, Genome Biol 2013;14(11):R125 |
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Mammary gland tumor | Mammary gland |
observed |
References: Deeb KK, Cancer Res 2007 Sep 1;67(17):8065-8080 ⋅ Herschkowitz JI, Proc Natl Acad Sci U S A 2012 Feb 21;109(8):2778-83 |
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Mammary gland tumor - basal-like | Mammary gland |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
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Mammary gland tumor - basal-like | Mammary gland | carboplatin ⋅ Taxol (paclitaxel) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
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Mammary gland tumor - basal-like | Mammary gland | sunitinib |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
Mammary gland tumor - basal-like | Mammary gland | selumetinib (AZD6244) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
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Mammary gland tumor - basal-like | Mammary gland | BEZ235 (NVP-BEZ235-AN) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
Mammary gland tumor - basal-like | Mammary gland | selumetinib (AZD6244) ⋅ BEZ235 (NVP-BEZ235-AN) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |