Strain SummaryC57BL/6-Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv

Strain Name	C57BL/6-Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv
Strain Type(s)	targeted mutation (conditional) • transgenic
Strain Synonym(s)	C57BL/6-Kras^tm4Tyj/+ Tg(Ipf1-cre)6Tuv • C57BL/6-Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv • Pdx1-Cre:Kras^G12D/+ • KC
Description	Heterozygous Kras, Tg(Pdx1-cre)6Tuv transgenic mice on a C57BL/6 background with possible contribution from FVB/N and 129S4/SvJae.
Strain Genetics	List all models in MMHCdb carrying the Tg(Pdx1-cre)6Tuv allele Tg(Pdx1-cre)6Tuv
	List all models in MMHCdb carrying the Kras^tm4Tyj allele Kras^tm4Tyj / Kras⁺

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Duct atypia	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas - Duct dysplasia	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas - Duct hyperplasia - epithelial	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas pancreatic intraepithelial neoplasia (PanIN) - high grade	Pancreas					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas pancreatic intraepithelial neoplasia (PanIN) - low grade	Pancreas					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas preneoplastic lesion	Pancreas					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9

Models