Strain SummaryB6;129S-Ager^tm1.1Arnd Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv

Strain Name	B6;129S-Ager^tm1.1Arnd Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knockout) • transgenic
Strain Synonym(s)	B6;129S/SvEv-Ager^tm1.1Arnd Kras^tm4Tyj/+ Tg(Ipf1-cre)6Tuv • B6;129S/SvEv-Ager^tm1.1Arnd Kras^tm4Tyj/+ Tg(Pdx1-cre)6Tuv • KCR
Description	Homozygous Ager, heterozygous Kras, Tg(Pdx1-cre)6Tuv transgenic mice on a mixed C57BL/6, 129S background. The 129S/SvEv substrain was not detailed. There are also possible contributions from 129P2/OlaHsd and FVB/N.
Strain Genetics	List all models in MMHCdb carrying the Tg(Pdx1-cre)6Tuv allele Tg(Pdx1-cre)6Tuv
	List all models in MMHCdb carrying the Kras^tm4Tyj allele Kras^tm4Tyj / Kras⁺
	List all models in MMHCdb carrying the Ager^tm1.1Arnd allele Ager^tm1.1Arnd / Ager^tm1.1Arnd

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Duct atypia	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas - Duct dysplasia	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas - Duct hyperplasia - epithelial	Pancreas - Duct					observed	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9
Pancreas pancreatic intraepithelial neoplasia (PanIN)	Pancreas					0	References: Vernon PJ, J Immunol 2013 Feb 1;190(3):1372-9

Models