Strain Summary(A/J x C57BL/6)F1-Trp53tm3.1Glo/+

Strain Name

(A/J x C57BL/6)F1-Trp53tm3.1Glo/+

Strain Type(s)

hybrid  •  targeted mutation (knock-in)

Strain Synonym(s)

A/J  •  A/J C57Bl/6 F-1 hybrid Trp53R172H heterozygote  •  A/J C57Bl/6 F-1 p53 R172H  •  A/J F-1

Description

Heterozygous mice. The genetic background of these mice was (A/J x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt+ from the original generation of the mutant allele.

Strain Genetics

Trp53tm3.1Glo / Trp53+

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue tumor Adipose tissue

20

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

Blood vessel hemangioma Blood vessel

0

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

Bone osteosarcoma Bone

17

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

Leukocyte lesion Leukocyte

10

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

7

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

(Unspecified organ) adenocarcinoma (Unspecified organ)

3

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

(Unspecified organ) carcinoma (Unspecified organ)

0

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

(Unspecified organ) tumor (Unspecified organ)

59

69

3 - 63

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

(Unspecified organ) tumor - malignant (Unspecified organ)

87

References: Chan CS, Life Sci Alliance 2021 Mar;4(3):