Strain Summary(A/J x C57BL/6)F1-Trp53tm3.1Glo/+
Strain Name |
(A/J x C57BL/6)F1-Trp53tm3.1Glo/+ |
Strain Type(s) |
hybrid • targeted mutation (knock-in) |
Strain Synonym(s) |
A/J • A/J C57Bl/6 F-1 hybrid Trp53R172H heterozygote • A/J C57Bl/6 F-1 p53 R172H • A/J F-1 |
Description |
Heterozygous mice. The genetic background of these mice was (A/J x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt+ from the original generation of the mutant allele. |
Strain Genetics |
Trp53tm3.1Glo / Trp53+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adipose tissue tumor | Adipose tissue |
20 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Blood vessel hemangioma | Blood vessel |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Bone osteosarcoma | Bone |
17 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Leukocyte lesion | Leukocyte |
10 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
7 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) adenocarcinoma | (Unspecified organ) |
3 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) carcinoma | (Unspecified organ) |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) tumor | (Unspecified organ) |
59 |
69 |
3 - 63 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) tumor - malignant | (Unspecified organ) |
87 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |