Strain SummaryAKR/J

Strain Name

 AKR/J

Strain Type(s)

 inbred

Strain Synonym(s)

 Afb  •  Ak  •  AK  •  Akm  •  AKR  •  AKR/Jax  •  AKR/J, H-2k  •  RIL  •  R.I.L.  •  Rockefeller Institute Leukemia

Strain Links

 • Mouse Phenome Database (MPD)
• Festing's List of Inbred Strains
• JAX Mice

Strain Genetics

 H2k / H2k
Krasb / Krasb

Models

48 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

13

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50   ⋅   Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

0

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal azoxymethane (AOM)

0

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50   ⋅   Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

References: Guda K, Cancer Lett 2003 Feb 28;191(1):17-25

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Large Intestine tumor Intestine - Large Intestine dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Small Intestine adenoma Intestine - Small Intestine

2.7

References: Shoemaker AR, Proc Natl Acad Sci U S A 1998 Sep 1;95(18):10826-31

Intestine - Small Intestine tumor Intestine - Small Intestine azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Small Intestine tumor Intestine - Small Intestine

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Kidney tumor Kidney azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Kidney tumor Kidney

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus

0 - 78

References: Angel JM, J Natl Cancer Inst 1989 Nov 1;81(21):1652-5

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus N-methyl-N-nitrosourea (MNU)

84

References: Angel JM, J Natl Cancer Inst 1989 Nov 1;81(21):1652-5

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mucenski ML, J Virol 1988 Mar;62(3):839-46

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Stomach

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

4 pathology image(s)
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Lung

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

2 pathology image(s)
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Skin

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

observed

References: Russell ES, 1966;():511-519

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

15 - 100

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte

34 - 50

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

20

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte leukemia Leukocyte

10 - 100

81

observed - 74

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70   ⋅   Myers DD, Life Sci 1970;9(Pt II):1071-80   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():   ⋅   Storer JB, J Gerontol 1966 Jul;21(3):404-9

Leukocyte leukemia Leukocyte Friend leukemia virus - "regressing" (RFV)

24 - 40

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte Friend leukemia virus - "conventional" (CFV)

30 - 52.5

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte 1-ethyl-1-nitrosourea (ENU)

44

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Leukocyte lymphoma Thymus 3-methylcholanthrene (MCA) (3-MC)

observed

References: Whitmire CE, J Natl Cancer Inst 1971 Dec;47(6):1255-65

Leukocyte lymphoma Leukocyte

observed

References: Staats J, Cancer Res 1985 Mar;45(3):945-77

Leukocyte lymphoma - lymphosarcoma Intestine - Small Intestine - Jejunum

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)
Leukocyte lymphoma - lymphosarcoma Intestine - Small Intestine - Duodenum

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)
Liver tumor Liver azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Liver tumor Liver

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Lung adenoma Lung 1-ethyl-1-nitrosourea (ENU)

14

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Lung adenoma Lung

0

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Lung adenoma Lung urethane (ethyl carbamate)

0

References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6

Lung carcinoma Lung N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Lung tumor Lung

5

References: Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7

Lung tumor Lung urethane (ethyl carbamate)

0

References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93

Lymphoid tissue lymphoma - lymphosarcoma Lymphoid tissue

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Sites of Metastasis: CNS - Meninges , Epididymis , Heart , Intestine - Large Intestine - Cecum , Intestine - Small Intestine - Duodenum , Intestine - Small Intestine - Jejunum , Kidney , Liver , Lung , Muscle - Striated - Skeletal , Pancreas , Spleen , Stomach

2 pathology image(s)
Mammary gland adenocarcinoma Mammary gland

observed

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal

0

References: Sher RB, PLoS One 2011;6(8):e23498

Ovary - Granulosa cell tumor Ovary - Granulosa cell

0

References: Beamer WG, Cancer Res 1988 Sep 15;48(18):5092-5

Skin tumor Skin 3-methylcholanthrene (MCA) (3-MC)

21

References: Whitmire CE, J Natl Cancer Inst 1971 Dec;47(6):1255-65

Thymus lymphoma Thymus

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

(Unspecified organ) tumor (Unspecified organ)

91

81

References: Storer JB, J Gerontol 1966 Jul;21(3):404-9