Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-08-18
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Expanded View
 
Strain
AKR/J
Strain Synonyms Afb  •  Ak  •  AK  •  Akm  •  AKR  •  AKR/Jax  •  AKR/J, H-2k  •  RIL  •  R.I.L.  •  Rockefeller Institute Leukemia
Strain Tumor Overview Collapsed View
Tumors 48 unique tumor sub-types displayed.

A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.

Tumor Name Organ(s) Affected Treatment Type
Agents
Metastasizes
To
References Number of
Tumor Sub-type Records
Frequency Range
Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal Chemical/Drug
azoxymethane (AOM)
  J:49937 1 13
Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal None (spontaneous)
  J:49937 1 0
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal Chemical/Drug
azoxymethane (AOM)
  J:49937
J:80268
2 observed
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal None (spontaneous)
  J:49937 1 0
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal Chemical/Drug
azoxymethane (AOM)
  J:80268 1 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal Chemical/Drug
azoxymethane (AOM)
  J:49937
J:80268
2 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal None (spontaneous)
  J:49937 1 0
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
azoxymethane (AOM)
  J:81930 1 observed
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
azoxymethane (AOM)
  J:242437 1 100
Intestine - Large Intestine tumor Intestine - Large Intestine Chemical/Drug
azoxymethane (AOM)
dextran sulfate sodium (DSS)
  J:242437 1 100
Intestine - Small Intestine adenoma Intestine - Small Intestine None (spontaneous)
  J:49809 1 2.7
Intestine - Small Intestine tumor Intestine - Small Intestine Chemical/Drug
azoxymethane (AOM)
  J:49937 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous)
  J:49937 1 0
Kidney tumor Kidney Chemical/Drug
azoxymethane (AOM)
  J:49937 1 0
Kidney tumor Kidney None (spontaneous)
  J:49937 1 0
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus None (spontaneous)
  J:10061 2 0 - 78
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:10061 1 84
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte None (spontaneous)
  J:235854
J:25442
2 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Stomach None (spontaneous)
  J:122261 1 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Lung None (spontaneous)
  J:122261 1 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Skin None (spontaneous)
  J:122261 1 observed
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous)
  J:2470 1 observed
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 4 15 - 100
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte None (spontaneous)
  J:109061 2 34 - 50
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 20
Leukocyte leukemia Leukocyte None (spontaneous)
  J:22621
J:22741
J:235854
J:24831
J:54944
J:55930
10 observed - 100
Leukocyte leukemia Leukocyte Virus
Friend leukemia virus - "regressing" (RFV)
  J:25401 2 24 - 40
Leukocyte leukemia Leukocyte Virus
Friend leukemia virus - "conventional" (CFV)
  J:25401 2 30 - 52.5
Leukocyte leukemia Leukocyte Chemical/Drug
1-ethyl-1-nitrosourea (ENU)
  J:24831 1 44
Leukocyte lymphoma Thymus Chemical/Drug
3-methylcholanthrene (MCA) (3-MC)
  J:35684 1 observed
Leukocyte lymphoma Leukocyte None (spontaneous)
  J:50296 1 observed
Leukocyte lymphoma - lymphosarcoma Intestine - Small Intestine - Jejunum None (spontaneous)
  J:122261 1 observed
Leukocyte lymphoma - lymphosarcoma Intestine - Small Intestine - Duodenum None (spontaneous)
  J:122261 1 observed
Liver tumor Liver Chemical/Drug
azoxymethane (AOM)
  J:49937 1 0
Liver tumor Liver None (spontaneous)
  J:49937 1 0
Lung adenoma Lung Chemical/Drug
1-ethyl-1-nitrosourea (ENU)
  J:24831 1 14
Lung adenoma Lung None (spontaneous)
  J:24831 1 0
Lung adenoma Lung Chemical/Drug
urethane (ethyl carbamate)
  J:7050 1 0
Lung carcinoma Lung Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 0
Lung tumor Lung None (spontaneous)
  J:17778 1 5
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
  J:16946 1 0
Lymphoid tissue lymphoma - lymphosarcoma Lymphoid tissue None (spontaneous)
CNS - Meninges
Epididymis
Heart
Intestine - Large Intestine - Cecum
Intestine - Small Intestine - Duodenum
Intestine - Small Intestine - Jejunum
Kidney
Liver
Lung
Muscle - Striated - Skeletal
Pancreas
Spleen
Stomach
J:122261 14 observed
Mammary gland adenocarcinoma Mammary gland None (spontaneous)
  J:94314
J:94320
2 observed
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous)
  J:176506 1 0
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous)
  J:9301 1 0
Skin tumor Skin Chemical/Drug
3-methylcholanthrene (MCA) (3-MC)
  J:35684 1 21
Thymus lymphoma Thymus None (spontaneous)
  J:235854 1 observed
(Unspecified organ) tumor (Unspecified organ) None (spontaneous)
  J:22621 2 81 - 91
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=15
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/AKR.shtml
JAX Mice http://jaxmice.jax.org/strain/000648.html