Model DetailsLung adenocarcinoma

Model Name

Lung adenocarcinoma

Strain

A/J

Tumor Inducing Agent(s)

Diet, Chemical/Drug, None (spontaneous) : urethane (ethyl carbamate)

Tumor Synonyms

papillary adenocarcinoma  •  lung alveolar/bronchiolar adenocarcinoma  •  malignant adenocarcinoma  •  lung carcinoma  •  lung adenocarcinoma  •  lung lesion  •  solid adenocarcinoma  •  lung tumor  •  primary lung tumor  •  pulmonary neoplasm

Strain Synonyms

A  •  A/J-Jax  •  Strain A  •  A/J, H-2a  •  A/Lilly  •  A/Jax  •  AJ  •  strain A  •  A/Cloudman
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Lung Male

observed

~70-80 weeks
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
Sabourin CL, Exp Lung Res 1998 Jul-Aug;24(4):499-521
Lung Female

80%

(41 of 51 mice)
58 weeks
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung Female

58%

(21 of 36 mice)
58 weeks
  • Notes

    Reproductive Status: reproductive status not specified

Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung Unspecified

observed

58-74 weeks
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Belinsky SA, Carcinogenesis 1997 Jan;18(1):115-20
Lung Male

observed

24 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Bai F, Mol Carcinog 1998 Aug;22(4):258-64
Lung Male

0%

(0 of 23 mice)
24 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Bai F, Mol Carcinog 1998 Aug;22(4):258-64
Lung Unspecified

observed

12 months
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung Male

very high

12.5 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50
Lung Female

25%

(7 of 28 mice)
22 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung Female

48%

(12 of 25 mice)
22 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung Male

observed

48.5-51 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
  • Gene Expression Data
Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75