Model DetailsLiver tumor
Model Name |
Liver tumor | Strain |
C57BL/6J-Trp53tm1Tyj/+ Xpatm1Hvs |
Tumor Inducing Agent(s) |
Chemical/Drug : 2-acetamidofluorene (2-AAF) |
Tumor Synonyms |
liver tumor • liver, hepatocellular adenoma + hepatocellular carcinoma • liver, HCA + HCC |
Strain Synonyms |
XPA/p53 • Xpa-/-/p53+/- • C57Bl/6J-TgH(XPAIm)55Cmg x C57Bl/6J-TgH(p53Im)Δ26Cmg |
Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
---|---|---|---|---|---|
Liver | Male |
6.7% (1 of 15 mice) |
45-47 weeks |
|
van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27 |
Liver | Female |
26.7% (4 of 15 mice) |
45-47 weeks |
|
van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27 |