Model DetailsLiver tumor

Model Name

Liver tumor

Strain

C57BL/6J-Trp53tm1Tyj/+ Xpatm1Hvs

Tumor Inducing Agent(s)

Chemical/Drug : 2-acetamidofluorene (2-AAF)

Tumor Synonyms

liver tumor  •  liver, hepatocellular adenoma + hepatocellular carcinoma  •  liver, HCA + HCC

Strain Synonyms

XPA/p53  •  Xpa-/-/p53+/-  •  C57Bl/6J-TgH(XPAIm)55Cmg x C57Bl/6J-TgH(p53Im)Δ26Cmg
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Liver Male

6.7%

(1 of 15 mice)
45-47 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27
Liver Female

26.7%

(4 of 15 mice)
45-47 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27