PDX Model DetailsTM00914

PDX Model Summary
Model Details	Model ID (Previous ID) TM00914 (EN1057F) Initial Diagnosis Ovary serous adenocarcinoma Final Diagnosis Ovary serous adenocarcinoma Stage/Grade AJCC IV / Grade:3 Primary Site Ovary Sample Site Endometrium Tumor Type Metastatic
Related Models	PDX models TM00914, TM00913 and TM00916 originated from the same patient.
Patient	Sex Female Age (at time of tissue collection) 68 Race/Ethnicity White / Not Hispanic or Latino Treatment Naïve? Yes Current Smoker/Former Smoker Unknown / Unknown
Engraftment	Host Strain NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ (aka NSG or NOD Scid gamma) Sample Type Surgical resection (fragment) Engraftment Site no data

Molecular Data (Engrafted Tumor)
Variants	no variation plots
Gene Expression	Platforms: RNA_Seq Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV
CNV Plots
Tumor Mutation Burden	Sample EN1057F136P0051P1 from passage P1 has a TMB score of 3.23 TMB Range 0.0-304.42 (across all JAX PDX models; TMB > 22 is considered high)
Microsatellite Instability	Sample:EN1057F136P0051P1 from passage P1 Score:MSI-S
Gene Fusion	no data

PDX Model Summary