Strain SummaryC57BL/6-Krastm3Tyj/+
Strain Name |
C57BL/6-Krastm3Tyj/+ |
Strain Type(s) |
targeted mutation (knock-in) |
Strain Synonym(s) |
KrasLA2 |
Description |
Heterozygous Kras mice on a C57BL/6 background with contribution from 129S4/SvJae and C57BL/6Nci. Mice were backcrossed at least 6 times to C57BL/6. |
Strain Genetics |
Krastm3Tyj / Kras+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Lung adenocarcinoma | Lung |
0 |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
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| Lung adenocarcinoma | Lung | phenformin ⋅ gossypol |
0 |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
||||
| Lung adenoma | Lung |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
|||||
| Lung adenoma | Lung | phenformin ⋅ gossypol |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
||||
| Lung hyperplasia | Lung |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
|||||
| Lung hyperplasia | Lung | phenformin ⋅ gossypol |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
||||
| Lung tumor | Lung |
observed - 100 |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
|||||