Strain SummaryC57BL/6-Aldh1l1tm1b(KOMP)Wtsi Krastm3Tyj/+
Strain Name |
C57BL/6-Aldh1l1tm1b(KOMP)Wtsi Krastm3Tyj/+ |
Strain Type(s) |
targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
KrasLA2; Aldh1l1-/- |
Description |
Homozygous Aldh1l1, heterozygous Kras mice on a C57BL/6 background with contribution from 129S4/SvJae. |
Strain Genetics |
Aldh1l1tm1b(KOMP)Wtsi / Aldh1l1tm1b(KOMP)Wtsi |
| Krastm3Tyj / Kras+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Lung adenoma | Lung |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
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| Lung adenoma | Lung | phenformin |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
||||
| Lung hyperplasia | Lung |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
|||||
| Lung hyperplasia | Lung | phenformin |
observed |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
||||
| Lung tumor | Lung |
observed - 100 |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
|||||
| Lung tumor | Lung | phenformin |
observed - 100 |
References: Lee SH, Cancers (Basel) 2020 May 28;12(6): |
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