Strain Summary(SWR/J x C57BL/6)F1-Trp53tm3.1Glo/+
Strain Name |
(SWR/J x C57BL/6)F1-Trp53tm3.1Glo/+ |
Strain Type(s) |
hybrid • targeted mutation (knock-in) |
Strain Synonym(s) |
SWR • SWR C57Bl/6 F-1 hybrid Trp53R172H heterozygote • SWR C57Bl/6 F-1 p53 R172H • SWR F-1 |
Description |
Heterozygous mice. The genetic background of these mice was (SWR/J x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt+ from the original generation of the mutant allele. |
Strain Genetics |
Trp53tm3.1Glo / Trp53+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adipose tissue tumor | Adipose tissue |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Blood vessel hemangioma | Blood vessel |
1 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Bone osteosarcoma | Bone |
20 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Leukocyte lesion | Leukocyte |
30 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
4 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) adenocarcinoma | (Unspecified organ) |
11 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) carcinoma | (Unspecified organ) |
8 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) tumor | (Unspecified organ) |
96 |
62 |
4 - 73 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |