Tumor Genetics

Marker Symbol	Marker Name	Mouse Chromosome	Mutation Types	Genetic Change
Hras	Hras proto-oncogene, GTPase	7	Point mutation	nucleotide 182 (codon 61), CAA->CTA; Gln to Leu [Q61L]
Hras	Hras proto-oncogene, GTPase	7	Point mutation	nucleotide 181 (codon 61), CAA->AAA; Gln to Lys [Q61K]
Hras	Hras proto-oncogene, GTPase	7	Nonsense mutation	nucleotide 181 (codon 61), CAA->TAA; Gln to Stop
Kras	Kras proto-oncogene, GTPase	6	Point mutation	nucleotide 34 (codon 12), GGT->TGT; Gly to Cys [G12C]
Kras	Kras proto-oncogene, GTPase	6	Point mutation	nucleotide 35 (codon 12), GGT->GAT; Gly to Asp [G12D]
Kras	Kras proto-oncogene, GTPase	6	Point mutation	nucleotide 182 (codon 61), CAA->CTA; Gln to Leu [Q61L]