Model DetailsLiver hepatocellular carcinoma
Model Name |
Liver hepatocellular carcinoma | Strain |
CD-1 |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
epithelial liver tumor • liver, hepatocellular carcinoma • liver tumor • liver hepatocellular carcinoma • liver carcinoma • liver neoplasm • liver, carcinoma, hepatocellular • hepatocellular carcinoma |
Strain Synonyms |
outbred CD-1 • Swiss CD-1® • CD1 nontransgenic • Charles River CD-1 • Swiss CD-1 • Crl:CD-1®(ICR) • outbred CD1 • (Swiss) CD-1 • CD1 • Crl:CD-1(ICR)BR • ICR Crj:CD-1 • random-bred Crl:CD-1(ICR)BR • CD-1 outbred • Crl:CD-1 (ICR) BR • Crj:CD-1(ICR) • ICR(CD-1) • Crl: CD-1 (ICR) BR • ICR |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Liver | Male |
0% (0 of 49 mice) |
57 weeks |
|
Takahashi O, Toxicology 1997 Dec 26;124(2):95-103 |
| Liver | Male |
0% (0 of 3 mice) |
<57 weeks |
|
Takahashi O, Toxicology 1997 Dec 26;124(2):95-103 |
| Liver | Female |
0% (0 of 50 mice) |
57 weeks |
|
Takahashi O, Toxicology 1997 Dec 26;124(2):95-103 |
| Liver | Female |
0% (0 of 1 mice) |
<57 weeks |
|
Takahashi O, Toxicology 1997 Dec 26;124(2):95-103 |
| Liver | Male |
2.8% |
|
Baldrick P, Toxicol Pathol 2007;35(4):562-9 | |
| Liver | Male |
3.2% |
|
Baldrick P, Toxicol Pathol 2007;35(4):562-9 | |
| Liver | Female |
0.4% |
|
Baldrick P, Toxicol Pathol 2007;35(4):562-9 | |
| Liver | Female |
0% |
|
Baldrick P, Toxicol Pathol 2007;35(4):562-9 | |
| Liver | Female |
0% (0 of 33 mice) |
90 weeks |
|
Waalkes MP, Cancer Res 2006 Feb 1;66(3):1337-45 |
| Liver | Male |
5.7% (41 of 725 mice) |
|
Chandra M, Toxicol Lett 1992 Jun;61(1):67-74 | |
| Lung | Male |
2.5% (18 of 725 mice) |
|
Chandra M, Toxicol Lett 1992 Jun;61(1):67-74 | |
| Liver | Female |
0.7% (5 of 725 mice) |
|
Chandra M, Toxicol Lett 1992 Jun;61(1):67-74 | |
| Lung | Female |
0.3% (2 of 725 mice) |
|
Chandra M, Toxicol Lett 1992 Jun;61(1):67-74 | |
| Liver | Male |
4.3% (3 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
4.3% (3 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
4.7% (3 of 64 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
1.4% (1 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
2.9% (2 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
11.4% (8 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
10% (7 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
8.6% (6 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
12.9% (9 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
11.4% (8 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
1.4% (1 of 72 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
6.7% (51 of 766 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
5.7% (4 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
5.7% (4 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
3.1% (2 of 64 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
8.6% (6 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
1.4% (1 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
7.1% (5 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
4.3% (3 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
7.1% (5 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
2.9% (2 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
8.6% (6 of 70 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
5.6% (4 of 72 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
5.5% (42 of 766 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
9.1% (81 of 891 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Female |
0.9% (8 of 890 mice) |
up to 109 weeks |
|
Maita K, Toxicol Pathol 1988;16(3):340-9 |
| Liver | Male |
1.7% (1 of 60 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Lung | Male |
0% (0 of 1 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Liver | Male |
3.3% (2 of 60 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Lung | Male |
0% (0 of 2 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Liver | Female |
0% (0 of 60 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Liver | Female |
1.7% (1 of 60 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Lung | Female |
0% (0 of 1 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Liver | Male |
1.7% (1 of 60 mice) |
|
Tannehill-Gregg SH, Toxicol Sci 2007 Jul;98(1):258-70 | |
| Liver | Male |
observed |
≥1 year |
|
Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |