Model DetailsLeukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma

Model Name

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma

Strain

(C57BL/6N x C3H/HeN)F1

Tumor Inducing Agent(s)

None (spontaneous)

Tumor Synonyms

histiocytic sarcoma  •  hematopoietic/lymphoreticular system, histiocytic sarcoma

Strain Synonyms

BCF1  •  B6C3F1  •  C57BL/6NxC3H/HeN F1  •  B6C3F1  •  (C57BL/6N X C3H/HeN)F1
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Leukocyte - Monocyte - Macrophage - Histiocyte Male

3.8%

(8 of 213 mice)
120 weeks
  • Notes

    Reproductive Status: reproductive status not specified

Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60
Leukocyte - Monocyte - Macrophage - Histiocyte Female

4.7%

(10 of 213 mice)
120 weeks
  • Notes

    Reproductive Status: reproductive status not specified

Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 41 mice)
12-24 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 15 mice)
30 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

7.1%

(1 of 14 mice)
36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

1.4%

(1 of 70 mice)
12-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

9.4%

(3 of 32 mice)
24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

7.5%

(3 of 40 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

9.6%

(7 of 73 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

15.8%

(3 of 19 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

9.8%

(13 of 132 mice)
12-36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 16 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 22 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.9%

(1 of 17 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 1 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

1.8%

(1 of 56 mice)
12-42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.8%

(15 of 258 mice)
12-42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 43 mice)
12-24 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 15 mice)
30 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 15 mice)
36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 73 mice)
12-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

5.3%

(1 of 19 mice)
24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

3.6%

(1 of 28 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

14.9%

(7 of 47 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

5.9%

(2 of 34 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

28.6%

(2 of 7 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

10.3%

(12 of 116 mice)
12-42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 11 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

9.5%

(2 of 21 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

18.75%

(3 of 16 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 8 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

8.9%

(5 of 56 mice)
12-42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

6.9%

(17 of 245 mice)
12-42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76