Model DetailsLeukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma

Model Name

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma

Strain

(C57BL/6N x C3H/HeN)F1

Tumor Inducing Agent(s)

Diet : calorie restricted

Tumor Synonym

histiocytic sarcoma

Strain Synonyms

BCF1  •  B6C3F1  •  C57BL/6NxC3H/HeN F1  •  B6C3F1  •  (C57BL/6N X C3H/HeN)F1
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 42 mice)
12-24 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 15 mice)
30 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 15 mice)
36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 22 mice)
42-48 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 94 mice)
12-48 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 7 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

15%

(3 of 20 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.9%

(2 of 34 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.0%

(2 of 40 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

3.6%

(2 of 55 mice)
42-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

6.0%

(7 of 116 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 3 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

0%

(0 of 3 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

6.7%

(1 of 15 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.3%

(1 of 19 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

6.7%

(1 of 15 mice)
48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.9%

(2 of 34 mice)
42-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

5.5%

(3 of 55 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Female

3.8%

(10 of 265 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 42 mice)
12-24 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 15 mice)
30 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 15 mice)
36 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

5.3%

(1 of 19 mice)
42 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

15.4%

(2 of 13 mice)
48 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

9.4%

(3 of 32 mice)
42-48 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

2.9%

(3 of 104 mice)
12-48 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 3 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

44.4%

(4 of 9 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

10%

(2 of 20 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

3.7%

(1 of 27 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

1.4%

(1 of 70 mice)
42-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

6.9%

(7 of 102 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 4 mice)
12-24 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

0%

(0 of 3 mice)
30 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

23.1%

(3 of 13 mice)
36 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

10%

(1 of 10 mice)
42 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

11.5%

(3 of 26 mice)
48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

11.1%

(4 of 36 mice)
42-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

12.5%

(7 of 56 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76
Leukocyte - Monocyte - Macrophage - Histiocyte Male

6.5%

(17 of 262 mice)
12-48 +/- 3 months
  • Treatment Notes
  • Notes

    Reproductive Status: virgin

Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76