Model DetailsLiver hepatocellular carcinoma
Model Name |
Liver hepatocellular carcinoma | Strain |
(C57BL/6N x C3H/HeN)F1 |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
hepatocellular carcinoma mesenteric lymph node metastasis • liver, hepatocellular carcinoma • hepatocellular neoplasm • hepatocellular carcinoma heart metastasis • liver hepatocellular carcinoma • hepatocellular carcinoma metastasis • liver carcinoma • hepatocellular carcinoma lung metastasis • hepatocellular carcinoma abdominal cavity metastasis • hepatocellular carcinoma • liver hepatocellular carcinoma (HCC) • hepatocellular carcinoma kidneymetastasis |
Strain Synonyms |
BCF1 • B6C3F1 • C57BL/6NxC3H/HeN F1 • B6C3F1 • (C57BL/6N X C3H/HeN)F1 |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Liver | Male |
16.4% (35 of 213 mice) |
120 weeks |
|
Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
| Liver | Female |
4.2% (9 of 213 mice) |
120 weeks |
|
Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
| Liver | Male |
23.8% (58 of 244 mice) |
2 years |
|
Tamano S, Toxicol Pathol 1988;16(3):321-6 |
| (Unspecified organ) | Male |
20.7% (12 of 58 mice) |
2 years |
|
Tamano S, Toxicol Pathol 1988;16(3):321-6 |
| Liver | Female |
4.5% (11 of 246 mice) |
2 years |
|
Tamano S, Toxicol Pathol 1988;16(3):321-6 |
| (Unspecified organ) | Female |
18.2% (2 of 11 mice) |
2 years |
|
Tamano S, Toxicol Pathol 1988;16(3):321-6 |
| Liver | Female |
6.7% (1 of 15 mice) |
30 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
7.1% (1 of 14 mice) |
36 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
12.5% (4 of 32 mice) |
24 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
6.8% (5 of 73 mice) |
30 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
5.3% (1 of 19 mice) |
36 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
7.7% (1 of 13 mice) |
36 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Female |
5.0% (13 of 258 mice) |
12-42 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| (Unspecified organ) | Female |
53.8% (7 of 13 mice) |
12-42 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
14.3% (2 of 14 mice) |
18 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
13.3% (2 of 15 mice) |
24 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
6.7% (1 of 15 mice) |
30 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
6.7% (1 of 15 mice) |
36 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
25% (2 of 8 mice) |
18 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
15.8% (3 of 19 mice) |
24 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
25.5% (12 of 47 mice) |
30 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
17.6% (6 of 34 mice) |
36 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
100% (1 of 1 mice) |
18 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
37.5% (3 of 8 mice) |
24 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
23.8% (5 of 21 mice) |
30 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
12.5% (2 of 16 mice) |
36 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
16.3% (40 of 245 mice) |
12-42 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| (Unspecified organ) | Male |
30% (12 of 40 mice) |
12-42 +/- 3 months |
|
Sheldon WG, Toxicol Pathol 1995 Jul-Aug;23(4):458-76 |
| Liver | Male |
13.72% (349 of 2543 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Lung | Male |
1.69% (43 of 2543 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Liver | Female |
2.3% (58 of 2522 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Lung | Female |
0.28% (7 of 2522 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Liver | Mixed Population |
8.04% (407 of 5065 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Abdominal cavity | Mixed Population |
1% |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Heart | Mixed Population |
1% |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Kidney | Mixed Population |
3% |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Lung | Mixed Population |
0.99% (50 of 5065 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Lymph node - Mesenteric | Mixed Population |
3% |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| (Unspecified organ) | Mixed Population |
observed |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Liver | Male |
13.72% (349 of 2543 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Liver | Female |
2.3% (58 of 2522 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |
| Liver | Mixed Population |
8.04% (407 of 5065 mice) |
94-114 weeks |
|
Ward JM, J Natl Cancer Inst 1979 Sep;63(3):849-54 |